Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.55 |
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | CTSS | P25774 | 2/20 | 0.53 |
| ▸ | CTSK | P43235 | 5/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 2/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | ECE1 | P42892 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3624630 | 1.00 | FOLH1 (0.55) | FOLH1CTSLCTSSCTSKCTSB | |
| SCHEMBL7286347 | 1.00 | FOLH1 (0.55) | FOLH1CTSLCTSSCTSKCTSB | |
| SCHEMBL21221151 | 0.95 | FOLH1 (0.52) | FOLH1CTSLCTSSCTSKCTSB | |
| SCHEMBL16441100 | 0.95 | FOLH1 (0.52) | FOLH1CTSLCTSSCTSKCTSB | |
| SCHEMBL21232384 | 0.95 | FOLH1 (0.52) | FOLH1CTSLCTSSCTSKCTSB | |
| SCHEMBL31243057 | 0.92 | CTSL (0.57) | FOLH1CTSLCTSSCTSKSIRT2 | |
| SCHEMBL2921260 | 0.92 | FOLH1 (0.59) | FOLH1CTSLCTSSCTSKCTSB | |
| SCHEMBL7624700 | 0.92 | FOLH1 (0.59) | FOLH1CTSLCTSSCTSKCTSB | |
| SCHEMBL677997 | 0.92 | FOLH1 (0.59) | FOLH1CTSLCTSSCTSKCTSB | |
| SCHEMBL28704605 | 0.91 | BCHE (0.58) | CTSLCTSSCTSKCASP1SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141995-B1 | COMPOSITIONS AND THEIR USES IN PROTECTING CELLS FROM TOXIC EXPOSURES | PERSCITUS BIOSCIENCES LLC (US) | 2014-11-05 | — | — | EP | disclosed |
| EP-2141995-B1 | COMPOSITIONS AND THEIR USES IN PROTECTING CELLS FROM TOXIC EXPOSURES | PERSCITUS BIOSCIENCES LLC (US) | 2014-11-05 | — | — | EP | disclosed |
| US-8435956-B2 | Compositions and methods for protecting cells from toxic exposures | PERCITUS BIOSCIENCES, LLC (US) | 2013-05-07 | — | — | US | disclosed |
| US-8435956-B2 | Compositions and methods for protecting cells from toxic exposures | PERCITUS BIOSCIENCES, LLC (US) | 2013-05-07 | — | — | US | disclosed |
| US-8435956-B2 | Compositions and methods for protecting cells from toxic exposures | PERCITUS BIOSCIENCES, LLC (US) | 2013-05-07 | — | — | US | disclosed |
| US-20120252764-A1 | COMPOSITIONS AND METHODS FOR PROTECTING CELLS FROM TOXIC EXPOSURES | PERSCITUS BIOSCIENCES, LLC (US) | 2012-10-04 | — | — | US | disclosed |
| US-20120252764-A1 | COMPOSITIONS AND METHODS FOR PROTECTING CELLS FROM TOXIC EXPOSURES | PERSCITUS BIOSCIENCES, LLC (US) | 2012-10-04 | — | — | US | disclosed |
| US-20120252764-A1 | COMPOSITIONS AND METHODS FOR PROTECTING CELLS FROM TOXIC EXPOSURES | PERSCITUS BIOSCIENCES, LLC (US) | 2012-10-04 | — | — | US | disclosed |
| EP-2141995-A1 | COMPOSITIONS AND METHODS FOR PROTECTING CELLS FROM TOXIC EXPOSURES | Perscitus Biosciences, LLC (US) | 2010-01-13 | — | — | EP | disclosed |
| US-20080253997-A1 | COMPOSITIONS AND METHODS FOR PROTECTING CELLS FROM TOXIC EXPOSURES | PERSCITUS BIOSCIENCES, LLC (US) | 2008-10-16 | — | — | US | disclosed |
| US-20080253997-A1 | COMPOSITIONS AND METHODS FOR PROTECTING CELLS FROM TOXIC EXPOSURES | PERSCITUS BIOSCIENCES, LLC (US) | 2008-10-16 | — | — | US | disclosed |
| US-20080253997-A1 | COMPOSITIONS AND METHODS FOR PROTECTING CELLS FROM TOXIC EXPOSURES | PERSCITUS BIOSCIENCES, LLC (US) | 2008-10-16 | — | — | US | disclosed |
| WO-2008119032-A1 | COMPOSITIONS AND METHODS FOR PROTECTING CELLS FROM TOXIC EXPOSURES | PERSCITUS BIOSCIENCES, LLC (US) | 2008-10-02 | — | — | WO | disclosed |
| WO-2008119032-A1 | COMPOSITIONS AND METHODS FOR PROTECTING CELLS FROM TOXIC EXPOSURES | PERSCITUS BIOSCIENCES, LLC (US) | 2008-10-02 | — | — | WO | disclosed |
| EP-1224186-B1 | PYRIDYL-CONTAINING SPIROCYCLIC COMPOUNDS AS INHIBITORS OF FIBRINOGEN-DEPENDENT PLATELET AGGREGATION | MILLENNIUM PHARM INC (US) | 2003-09-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120252764-A1 | COMPOSITIONS AND METHODS FOR PROTECTING CELLS FROM TOXIC EXPOSURES | PRDX5, GPX1, GPX4 | FOLH1 1113/4885CTSL 2335/4885CTSS 1149/4885 |
| US-20080253997-A1 | COMPOSITIONS AND METHODS FOR PROTECTING CELLS FROM TOXIC EXPOSURES | PRDX5, GPX1, GPX4 | FOLH1 1113/4885CTSL 2335/4885CTSS 1149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.