SCHEMBL677997

SCHEMBL677997

O=C(O)CC[C@H](NC(=O)OCc1ccccc1)C(=O)OCc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 3/20 0.59
CASP1 P29466 5/20 0.55
HTT P42858 1/20 0.55
MME P08473 1/20 0.55
ECE1 P42892 1/20 0.55
CTSK P43235 3/20 0.53
TACR1 P25103 2/20 0.53
CTRB1 P17538 2/20 0.52
CTSL P07711 1/20 0.52
CTSB P07858 1/20 0.52
CTSS P25774 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7624700 1.00 FOLH1 (0.59) FOLH1CASP1HTTMMEECE1
SCHEMBL2921260 1.00 FOLH1 (0.59) FOLH1CASP1HTTMMEECE1
SCHEMBL30902878 0.95 MME (0.56) FOLH1CASP1HTTMMEECE1
SCHEMBL10565196 0.93 FOLH1 (0.58) FOLH1CASP1HTTMMEECE1
SCHEMBL4910765 0.93 FOLH1 (0.58) FOLH1CASP1HTTMMEECE1
SCHEMBL3624634 0.92 FOLH1 (0.55) FOLH1CASP1MMEECE1CTSK
SCHEMBL3624630 0.92 FOLH1 (0.55) FOLH1CASP1MMEECE1CTSK
SCHEMBL21232384 0.92 FOLH1 (0.52) FOLH1CASP1MMEECE1CTSK
SCHEMBL21221151 0.92 FOLH1 (0.52) FOLH1CASP1MMEECE1CTSK
SCHEMBL7286347 0.92 FOLH1 (0.55) FOLH1CASP1MMEECE1CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9458188-B2 Efficient peptide couplings and their use in the synthesis and isolation of a cyclopenta (G) quinazoline trisodium salt BTG INTERNATIONAL LIMITED (GB) 2016-10-04 US claimed
EP-2655398-B1 EFFICIENT PEPTIDE COUPLINGS AND THEIR USE IN THE SYNTHESIS AND ISOLATION OF A CYCLOPENTA (G) QUINAZOLINE TRISODIUM SALT BTG INT LTD (GB) 2016-08-24 EP claimed
US-20130345423-A1 EFFICIENT PEPTIDE COUPLINGS AND THEIR USE IN THE SYNTHESIS AND ISOLATION OF A CYCLOPENTA (G) QUINAZOLINE TRISODIUM SALT Onyx Pharmaceutical, Inc. (US) 2013-12-26 US claimed
EP-2655398-A2 EFFICIENT PEPTIDE COUPLINGS AND THEIR USE IN THE SYNTHESIS AND ISOLATION OF A CYCLOPENTA (G) QUINAZOLINE TRISODIUM SALT Onyx Pharmaceuticals, Inc. (US) 2013-10-30 EP claimed
WO-2012087888-A2 EFFICIENT PEPTIDE COUPLINGS AND THEIR USE IN THE SYNTHESIS AND ISOLATION OF A CYCLOPENTA (G) QUINAZOLINE TRISODIUM SALT ONYX PHARMACEUTICALS, INC. (US) 2012-06-28 WO claimed
EP-0624599-B1 Derivatives of mono (6-amino-desoxy)cyclodextrin substituted in position 6 with an alpha aminoacid group, process of their preparation and applications OREAL (FR) 1997-07-30 EP claimed
US-12629423-B2 Olfactory delivery scaffolds using antisense oligonucleotides and methods for making and using same OLFERA CORPORATION (US) 2026-05-19 US disclosed
US-20260062447-A1 COMPOUNDS UNIV SOUTHAMPTON (GB) 2026-03-05 US disclosed
US-20260021190-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES MERCK SHARP & DOHME LLC (US) 2026-01-22 US disclosed
EP-4648799-A1 LIGAND-DRUG CONJUGATES Sun Pharma Advanced Research Company Ltd (IN) 2025-11-19 EP disclosed
EP-4642484-A1 TARGETED TREATMENT OF PROSTATE CANCERS AND OTHER TUMORS BY AN ANTIBODY-DRUG CONJUGATE Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP disclosed
EP-4615487-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES Merck Sharp & Dohme LLC (US) 2025-09-17 EP disclosed
US-20250269038-A1 Olfactory Delivery Scaffolds Using Antisense Oligonucleotides and Methods for Making and Using Same OLFERA CORPORATION 2025-08-28 US disclosed
WO-1988001650-A1 ENZYMATIC PROCESS CELLTECH LIMITED (GB) 1988-03-10 WO disclosed
EP-0189305-A2 Peptide derivatives ICI AMERICAS INC. (US) 1986-07-30 EP disclosed
US-4591459-A Intermediates for 6-(aminoacyloxymethyl) penicillanic acid 1,1-dioxides PFIZER INC. (US) 1986-05-27 US disclosed
US-4503040-A 6-(Aminoacyloxymethyl)penicillanic acid 1,1-dioxides as beta-lactamase inhibitors PFIZER INC. (US) 1985-03-05 US disclosed
EP-0052296-B1 GLUTAMINE DERIVATIVES USABLE FOR CURING IMMUNE DISEASES, METHODS FOR THEIR PREPARATION AND COMPOSITIONS COMPRISING SAID DERIVATIVES MITSUBISHI KASEI CORPORATION (JP) 1984-06-27 EP disclosed
US-4439448-A IMMUNOMODULATING ACTIVITY MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1984-03-27 US disclosed
EP-0052296-A1 Glutamine derivatives usable for curing immune diseases, methods for their preparation and compositions comprising said derivatives MITSUBISHI KASEI CORPORATION (JP) 1982-05-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250269038-A1 Olfactory Delivery Scaffolds Using Antisense Oligonucleotides and Methods for Making and Using Same OR51E2, OR10J3, GAP43 FOLH1 2912/4885CASP1 2135/4885HTT 152/4885
US-12629423-B2 Olfactory delivery scaffolds using antisense oligonucleotides and methods for making and using same OR10J3, OR51E2, TAS2R43 FOLH1 4180/4885CASP1 1200/4885HTT 793/4885
US-20260062447-A1 COMPOUNDS VHL, HIF1A, HYOU1 FOLH1 1894/4885CASP1 1704/4885HTT 2794/4885
US-20260021190-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES INSR, GPR119, GLP1R FOLH1 368/4885CASP1 3852/4885HTT 1719/4885
US-20130345423-A1 EFFICIENT PEPTIDE COUPLINGS AND THEIR USE IN THE SYNTHESIS AND ISOLATION OF A CYCLOPENTA (G) QUINAZOLINE TRISODIUM SALT GLUL, QPCT, GLS FOLH1 94/4885CASP1 4032/4885HTT 1140/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.