Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A2 | O00482 | 1/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.36 |
| ▸ | GSR | P00390 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3625966 | 0.84 | NR5A2 (0.36) | NR5A2NR5A1GSR | |
| SCHEMBL3622829 | 0.83 | NR5A2 (0.38) | NR5A2NR5A1 | |
| SCHEMBL3621214 | 0.82 | GSR (0.54) | NR5A2NR5A1GSR | |
| SCHEMBL3619585 | 0.82 | NR5A2 (0.42) | NR5A2NR5A1GSR | |
| SCHEMBL3617344 | 0.80 | NR5A2 (0.49) | NR5A2NR5A1HDAC3HDAC1HDAC2 | |
| SCHEMBL3618691 | 0.79 | NR5A2 (0.38) | NR5A2NR5A1HDAC4HDAC2HDAC8 | |
| SCHEMBL3621104 | 0.79 | CYP2C19 (0.37) | NR5A2NR5A1HDAC1GSR | |
| SCHEMBL3621681 | 0.78 | MPO (0.48) | HDAC1PTGS2 | |
| SCHEMBL3624485 | 0.78 | NR5A2 (0.44) | NR5A2NR5A1HDAC3HDAC1HDAC2 | |
| SCHEMBL3619703 | 0.78 | NR5A2 (0.44) | NR5A2NR5A1HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834062-B2 | Aminoalkylphenols, methods of using and making the same | MERCK SHARP & DOHME CORP. (US) | 2010-11-16 | — | — | US | disclosed |
| US-20090298949-A1 | AMINOALKYLPHENOLS, METHODS OF USING AND MAKING THE SAME | MERCK SHARP & DOHME LLC | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298949-A1 | AMINOALKYLPHENOLS, METHODS OF USING AND MAKING THE SAME | NPEPPS, PHOSPHO1, LNPEP | NR5A2 4732/4885NR5A1 4748/4885HDAC3 2630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.