SCHEMBL3625859

SCHEMBL3625859

CC(O)COc1c(Br)cc(C(C)(C)c2cc(Br)c(OCC(C)O)c(Br)c2)cc1Br

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.64
ALOX15 P16050 2/20 0.46
ALOX12 P18054 2/20 0.46
TSHR P16473 2/20 0.46
HIF1A Q16665 2/20 0.46
CYP3A4 P08684 1/20 0.46
HPGD P15428 1/20 0.46
CASP1 P29466 1/20 0.46
RECQL P46063 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CHEK1 O14757 1/20 0.40
DAPK3 O43293 1/20 0.40
RET P07949 1/20 0.40
PDGFRB P09619 1/20 0.40
PIM1 P11309 1/20 0.40
PDGFRA P16234 1/20 0.40
KDR P35968 1/20 0.40
MAPK8 P45983 1/20 0.40
RPS6KA3 P51812 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL679893 0.94 TSHR (0.58) ALDH1A1ALOX15ALOX12TSHRHIF1A
SCHEMBL14392240 0.94 ALDH1A1 (0.57) ALDH1A1ALOX15ALOX12TSHRHIF1A
SCHEMBL2688149 0.85 ALDH1A1 (0.62) ALDH1A1ALOX15ALOX12TSHRHIF1A
SCHEMBL12197650 0.83 ALDH1A1 (0.60) ALDH1A1ALOX15ALOX12TSHRHIF1A
SCHEMBL677415 0.83 ALDH1A1 (0.60) ALDH1A1ALOX15ALOX12TSHRHIF1A
SCHEMBL11516907 0.83 ALDH1A1 (0.60) ALDH1A1ALOX15ALOX12TSHRHIF1A
SCHEMBL14601519 0.83 ALDH1A1 (0.60) ALDH1A1ALOX15ALOX12TSHRHIF1A
SCHEMBL11116978 0.83 ALDH1A1 (0.44) ALDH1A1TSHRHIF1ALMNAMEN1
SCHEMBL11502472 0.82 ALDH1A1 (0.73) ALDH1A1ALOX15ALOX12TSHRHIF1A
SCHEMBL13207146 0.82 GLA (0.46) ALDH1A1TSHRHIF1ACYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100199491-A1 MANUFACTURING METHOD OF IMAGE PICK-UP DEVICE, IMAGE PICK-UP DEVICE AND OPTICAL ELEMENT KONICA MINOLTA OPTO, INC. (JP) 2010-08-12 US disclosed
EP-2166395-A1 IMAGING DEVICE MANUFACTURING METHOD, IMAGING DEVICE AND OPTICAL ELEMENT Konica Minolta Opto, Inc. (JP) 2010-03-24 EP disclosed
US-6740721-B2 HAVING LOW VISCOSITY AND CAPABLE OF YIELDING A CURED MATERIAL HAVING A HIGH REFRACTIVE INDEX AND SMALL SPECIFIC GRAVITY SHOWA DENKO K.K. (JP) 2004-05-25 US disclosed
CN-1466598-A Plastic lens composition, plastic lens and method for producing the plastic lens �Ѻ͵繤��ʽ���� 2004-01-07 CN disclosed
US-20030149141-A1 Plastic lens composition, plastic lens,and process for producing the plastic lens SHOWA DENKO K.K. (JP) 2003-08-07 US disclosed
US-4525529-A HALOGEN-CONTAINING COPOLYMERIC POLYESTER BLENDED WITH MODIFIED ETHYLENE COPOLYMER MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1985-06-25 US disclosed
US-4454302-A BLEND WITH HALOGEN CONTAINING ACRYLIC RESIN MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1984-06-12 US disclosed
US-4053439-A METAL SALT OF AROMATIC CARBOXYLATE ARMSTRONG CORK COMPANY (US) 1977-10-11 US disclosed
US-4046724-A FIBERS, HIGH MOLECULAR WEIGHT ORGANO-PHOSPHORUS COMPOUND TOYO BOSEKI KABUSHIKI KAISHA (JA) 1977-09-06 US disclosed