SCHEMBL679893

SCHEMBL679893

CC(O)COc1c(Br)cc(C(C)(C)c2cc(Br)c(O)c(Br)c2)cc1Br

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.58
ALOX15 P16050 3/20 0.58
HIF1A Q16665 3/20 0.58
HSD17B10 Q99714 3/20 0.58
ALDH1A1 P00352 2/20 0.58
ALOX12 P18054 2/20 0.58
CYP3A4 P08684 1/20 0.58
HPGD P15428 1/20 0.58
CASP1 P29466 1/20 0.58
RECQL P46063 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
CHEK1 O14757 1/20 0.46
DAPK3 O43293 1/20 0.46
RET P07949 1/20 0.46
PDGFRB P09619 1/20 0.46
PIM1 P11309 1/20 0.46
PDGFRA P16234 1/20 0.46
KDR P35968 1/20 0.46
MAPK8 P45983 1/20 0.46
RPS6KA3 P51812 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3625859 0.94 ALDH1A1 (0.64) TSHRALOX15HIF1AHSD17B10ALDH1A1
SCHEMBL14252079 0.89 HIF1A (0.59) TSHRALOX15HIF1AHSD17B10ALDH1A1
SCHEMBL23749724 0.89 ALOX15 (0.59) TSHRALOX15HIF1AHSD17B10ALDH1A1
SCHEMBL14392240 0.88 ALDH1A1 (0.57) TSHRALOX15HIF1AHSD17B10ALDH1A1
SCHEMBL20091584 0.85 ALDH1A1 (0.55) TSHRALOX15HIF1AHSD17B10ALDH1A1
SCHEMBL21917342 0.85 ALDH1A1 (0.55) TSHRALOX15HIF1AHSD17B10ALDH1A1
SCHEMBL14142904 0.85 ALDH1A1 (0.42) TSHRALOX15HIF1AHSD17B10ALDH1A1
SCHEMBL15788664 0.84 ALDH1A1 (0.54) TSHRALOX15HIF1AHSD17B10ALDH1A1
SCHEMBL14886924 0.84 THRB (0.41) TSHRALOX15HIF1AHSD17B10ALDH1A1
SCHEMBL12758368 0.82 ALDH1A1 (0.51) TSHRALOX15HIF1AHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11834574-B2 Dual cure additive manufacturing resins for production of flame retardant objects CARBON, INC. (US) 2023-12-05 US disclosed
US-20230128079-A1 ANTIMONY FREE FLAME-RETARDED EPOXY COMPOSITIONS BROMINE COMPOUNDS LTD. (IL) 2023-04-27 US disclosed
US-11560448-B2 Antimony free flame-retarded epoxy compositions BROMINE COMPOUNDS LTD. (IL) 2023-01-24 US disclosed
EP-3529306-B1 FLAME-RETARDED POLYESTER COMPOSITIONS BROMINE COMPOUNDS LTD (IL) 2022-06-29 EP disclosed
EP-3555230-B1 ANTIMONY FREE FLAME-RETARDED EPOXY COMPOSITIONS BROMINE COMPOUNDS LTD (IL) 2021-09-22 EP disclosed
US-11111376-B2 Flame-retarded styrene-containing formulations BROMINE COMPOUNDS LTD. (IL) 2021-09-07 US disclosed
EP-3601425-B1 FLAME-RETARDED STYRENE-CONTAINING COMPOSITIONS BROMINE COMPOUNDS LTD (IL) 2021-03-10 EP disclosed
EP-3601436-B1 FLAME-RETARDED STYRENE-CONTAINING FORMULATIONS BROMINE COMPOUNDS LTD (IL) 2021-01-13 EP disclosed
US-20200277488-A2 FLAME-RETARDED STYRENE-CONTAINING FORMULATIONS BROMINE COMPOUNDS LTD. (IL) 2020-09-03 US disclosed
US-10723833-B2 Reactive flame retardants for polyurethane and polyisocyanurate foams ICL-IP AMERICA INC. (US) 2020-07-28 US disclosed
US-7399431-B2 Material for neutron shielding and for maintaining sub-critically, process for its preparation and its applications COGEMA LOGISTICS (FR) 2008-07-15 US disclosed
US-20080160219-A1 Cellulose Ester Film. Polarizing Plate and Liquid-Crystal Display Device FUJIFILM CORPORATION (JP) 2008-07-03 US disclosed
US-20080064233-A1 CIRCUIT-CONNECTING MATERIAL AND CIRCUIT TERMINAL CONNECTED STRUCTURE AND CONNECTING METHOD HITACHI CHEMICAL CO., LTD. (JP) 2008-03-13 US disclosed
US-20080057742-A1 CIRCUIT-CONNECTING MATERIAL AND CIRCUIT TERMINAL CONNECTED STRUCTURE AND CONNECTING METHOD HITACHI CHEMICAL CO., LTD. (JP) 2008-03-06 US disclosed
US-20080054225-A1 interposed between circuit electrodes facing each other and electrically connects the electrodes in the pressing direction by pressing the facing electrodes against each other; the circuit-connecting material comprising as essential components, a curing agent and a hydroxy resin with radical polymer HITACHI CHEMICAL CO., LTD. (JP) 2008-03-06 US disclosed
US-20070299172-A1 interposed between circuit electrodes facing each other and electrically connects the electrodes in the pressing direction by pressing the facing electrodes against each other; the circuit-connecting material comprising as essential components, a curing agent and a hydroxy resin with radical polymer HITACHI CHEMICAL CO., LTD. (JP) 2007-12-27 US disclosed
WO-2007132463-A1 FLAME RETARDANT COMPOSITION BROMINE COMPOUNDS LTD. (IL) 2007-11-22 WO disclosed
US-20070155870-A1 Flame-retardant polyester fiber for artificial hair KANEKA CORPORATION (JP) 2007-07-05 US disclosed
US-20070020307-A1 Medical devices containing radiation resistant polymers BOSTON SCIENTIFIC SCIMED, INC. 2007-01-25 US disclosed
US-7160486-B2 Material based on vinylester resin for neutron shielding and maintenance of sub-criticality COGEMA LOGISTICS (FR) 2007-01-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10723833-B2 Reactive flame retardants for polyurethane and polyisocyanurate foams PFAS, PFKFB1, PFN1 TSHR 3812/4885ALOX15 1102/4885HIF1A 534/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.