SCHEMBL3625899

SCHEMBL3625899

C=Cc1ccc(CCN=C=O)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
MIF P14174 5/20 0.38
TRPA1 O75762 1/20 0.36
CYP2E1 P05181 1/20 0.36
CYP2A6 P11509 1/20 0.36
HIF1A Q16665 1/20 0.36
CYP2A13 Q16696 1/20 0.36
EPAS1 Q99814 1/20 0.36
CA1 P00915 7/20 0.36
CA2 P00918 7/20 0.36
CA9 Q16790 6/20 0.36
CA7 P43166 1/20 0.36
POLB P06746 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CA12 O43570 5/20 0.33
TSHR P16473 2/20 0.32
MEN1 O00255 1/20 0.32
TP53 P04637 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3618228 0.89 MIF (0.40) ALDH1A1MIFCA1CA2CA9
SCHEMBL3621874 0.88 MIF (0.41) ALDH1A1MIFCA1CA2CA9
SCHEMBL331135 0.84 MIF (0.48) MIFTRPA1CYP2E1CYP2A6HIF1A
SCHEMBL620052 0.81 ALDH1A1 (0.44) ALDH1A1MIFTRPA1CA1CA2
SCHEMBL9251367 0.80 MIF (0.41) ALDH1A1MIFTRPA1CYP2E1CYP2A6
SCHEMBL18567327 0.76 MIF (0.42) ALDH1A1MIFTRPA1CYP2E1CYP2A6
SCHEMBL1647493 0.75 ALDH1A1 (0.65) ALDH1A1CA1CA2POLBTDP1
SCHEMBL50012 0.75 ALDH1A1 (0.65) ALDH1A1CA1CA2POLBTDP1
SCHEMBL1846505 0.75 MIF (0.66) ALDH1A1MIFTRPA1CYP2E1CYP2A6
SCHEMBL1148243 0.75 TAAR1 (0.45) ALDH1A1MIFTRPA1CYP2E1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113929866-B Modified resin and resin composition 旭化成株式会社 2023-07-07 CN disclosed
CN-111205424-B Modified resin and resin composition 旭化成株式会社 2022-04-08 CN disclosed
CN-113929866-A Modified resin and resin composition 旭化成株式会社 2022-01-14 CN disclosed
WO-2021154692-A1 ACTINICALLY-CROSSLINKABLE POLYSILOXANE-POLYGLYCEROL BLOCK COPOLYMERS AND METHODS OF MAKING AND USE THEREOF Clearlab Sg Pte Ltd. (SG) 2021-08-05 WO disclosed
CN-107629183-B Modified resin and resin composition 旭化成株式会社 2021-01-05 CN disclosed
CN-111205424-A Modified resin and resin composition 旭化成株式会社 2020-05-29 CN disclosed
CN-1537876-B Multi-branch polymer, its production method and its application MITSU CHEMICALS INC 2013-01-16 CN disclosed
US-7795347-B2 Multi-branched polymer, process for producing the same, and applications thereof MITSUI CHEMICALS, INC. (JP) 2010-09-14 US disclosed
EP-1396504-B1 Polyolefin macromonomer, graft polymer obtained from the polyolefin macromonomer, and use thereof MITSUI CHEMICALS INC (JP) 2009-01-14 EP disclosed
EP-1457512-B1 Multi-branched polymer, process for producing the same, and applications thereof MITSUI CHEMICALS INC (JP) 2008-05-07 EP disclosed
US-7067587-B2 Polyolefin macromonomer, graft polymer obtained from the polyolefin macromonomer, and use thereof MITSUI CHEMICALS, INC. (JP) 2006-06-27 US disclosed
US-20040242791-A1 Polyolefin macromonomer, graft polymer obtained from the polyolefin macromonomer, and use thereof MITSUI CHEMICALS, INC. (JP) 2004-12-02 US disclosed
US-20040220346-A1 Multi-branched polymer, process for producing the same, and applications thereof MITSUI CHEMICALS, INC. (JP) 2004-11-04 US disclosed
CN-1537876-A Multi-branch polymer, its production method and its application ������ѧ��ʽ���� 2004-10-20 CN disclosed
EP-1457512-A1 Multi-branched polymer, process for producing the same, and applications thereof Mitsui Chemicals, Inc. (JP) 2004-09-15 EP disclosed
EP-1396504-A2 Polyolefin macromonomer, graft polymer obtained from the polyolefin macromonomer, and use thereof Mitsui Chemicals, Inc. (JP) 2004-03-10 EP disclosed
WO-2000078740-A1 SOLID-SUPPORTED INITIATORS AND FUNCTIONAL POLYMERS FOR USE IN ORGANIC SYNTHESIS AND COMBINATORIAL CHEMISTRY WARNER-LAMBERT COMPANY (US) 2000-12-28 WO disclosed
WO-1995000560-A1 REACTIVE POLYMERS JOHNSON, Karen, L. (US) 1995-01-05 WO disclosed