Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23744240 | 0.91 | MIF (0.39) | MIFTP53TDP1FAAHALDH1A1 | |
| SCHEMBL3628956 | 0.83 | TP53 (0.44) | MIFTP53TDP1TRPA1FAAH | |
| SCHEMBL6804290 | 0.82 | MIF (0.50) | MIFTRPA1CYP2E1CYP2A6HIF1A | |
| SCHEMBL3625899 | 0.80 | ALDH1A1 (0.41) | MIFTP53TDP1TRPA1CYP2E1 | |
| SCHEMBL595016 | 0.78 | TP53 (0.52) | TP53TDP1FAAHALDH1A1TSHR | |
| SCHEMBL29375309 | 0.78 | TP53 (0.52) | TP53TDP1FAAHALDH1A1TSHR | |
| SCHEMBL29619562 | 0.77 | TP53 (0.50) | TP53TDP1FAAHALDH1A1TSHR | |
| SCHEMBL1645656 | 0.77 | TP53 (0.50) | TP53TDP1FAAHALDH1A1TSHR | |
| SCHEMBL1851734 | 0.76 | HTR3E (0.54) | MIFALDH1A1HTR3EHTR3BHTR3A | |
| SCHEMBL29542006 | 0.76 | HTR3E (0.54) | MIFALDH1A1HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995000560-A1 | REACTIVE POLYMERS | JOHNSON, Karen, L. (US) | 1995-01-05 | — | — | WO | disclosed |