Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL2259927 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL292254 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL10773161 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL5918793 | 0.96 | FFAR3 (0.54) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL1054733 | 0.96 | — | — | |
| Acetic Acid SCHEMBL5182815 | 0.93 | FFAR3 (0.50) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL19128777 | 0.93 | FFAR3 (0.50) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL17459497 | 0.93 | FFAR3 (0.50) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL4937602 | 0.93 | FFAR3 (0.50) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetone SCHEMBL28344975 | 0.85 | ALDH1A1 (0.53) | FFAR3LCKFYNALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2053085-B1 | Rubber composition for a tire | YOKOHAMA RUBBER CO LTD (JP) | 2013-05-22 | — | — | EP | disclosed |
| US-7714049-B2 | Compounding agent for rubber vulcanization containing amine salt compound of carboxylic group-containing disulfide, method for producing the same, rubber composition containing the same and pneumatic tire using the same as rubber for belt coat and/or belt edge cush | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2010-05-11 | — | — | US | disclosed |
| US-20100004380-A1 | COMPOUNDING AGENT FOR RUBBER VULCANIZATION CONTAINING AMINE SALT COMPOUND OF CARBOXYLIC GROUP-CONTAINING DISULFIDE, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION CONTAINING THE SAME AND PNEUMATIC TIRE USING THE SAME AS RUBBER FOR BELT COAT AND/OR BELT EDGE CUSHION | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2010-01-07 | — | — | US | disclosed |
| EP-2053085-A1 | COMPOUNDING AGENT FOR RUBBER VULCANIZATION CONTAINING AMINE SALT COMPOUND OF CARBOXYLIC ACID GROUP-CONTAINING DISULFIDE, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION CONTAINING THE SAME, AND PNEUMATIC TIRE USING THE SAME IN RUBBER FOR BELT COAT AND/OR BELT EDGE CUSHION | The Yokohama Rubber Co., Ltd. (JP) | 2009-04-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004380-A1 | COMPOUNDING AGENT FOR RUBBER VULCANIZATION CONTAINING AMINE SALT COMPOUND OF CARBOXYLIC GROUP-CONTAINING DISULFIDE, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION CONTAINING THE SAME AND PNEUMATIC TIRE USING THE SAME AS RUBBER FOR BELT COAT AND/OR BELT EDGE CUSHION | SPIN4, SUPT16H, ITCH | FFAR3 4262/4885LCK 2819/4885FYN 2892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.