Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK2 | O95069 | 10/20 | 0.45 |
| ▸ | KCNK10 | P57789 | 8/20 | 0.42 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3627856 | 0.88 | CA1 (0.38) | KCNK2KCNK10KIF11CA1CA2 | |
| SCHEMBL3628825 | 0.84 | MAP2K2 (0.44) | KIF11CA1CA2ABCC9ABCC8 | |
| SCHEMBL3628210 | 0.84 | HDAC1 (0.51) | KCNK2KCNK10KIF11CA1CA2 | |
| SCHEMBL24246280 | 0.84 | CA1 (0.42) | KIF11CA1CA2ABCC9ABCC8 | |
| SCHEMBL31499928 | 0.81 | KCNK2 (0.43) | KCNK2KCNK10KIF11CA1CA2 | |
| SCHEMBL9359721 | 0.78 | HTT (0.57) | ALDH1A1MAPTHTT | |
| SCHEMBL31548138 | 0.78 | HTT (0.57) | ALDH1A1MAPTHTT | |
| SCHEMBL15049327 | 0.76 | PDK1 (0.47) | CA1CA2ABCC9ABCC8KCNJ11 | |
| SCHEMBL15072457 | 0.76 | KMT2A (0.58) | CA1CA2ALDH1A1LMNAMAPT | |
| SCHEMBL6555297 | 0.76 | NPC1 (0.56) | CA1CA2ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466321-B2 | 4-(trichloromethylthio) anilines, method for production thereof, and method for producing 4-(trifluoromethylthio) anilines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-06-18 | — | — | US | disclosed |
| US-8466321-B2 | 4-(trichloromethylthio) anilines, method for production thereof, and method for producing 4-(trifluoromethylthio) anilines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-06-18 | — | — | US | disclosed |
| EP-2174929-B1 | 4-(TRICHLOROMETHYLTHIO)ANILINE, METHOD FOR PRODUCING THE SAME, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO)ANILINE | SUMITOMO CHEMICAL CO (JP) | 2013-03-27 | — | — | EP | disclosed |
| EP-2174929-B1 | 4-(TRICHLOROMETHYLTHIO)ANILINE, METHOD FOR PRODUCING THE SAME, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO)ANILINE | SUMITOMO CHEMICAL CO (JP) | 2013-03-27 | — | — | EP | disclosed |
| US-8399707-B2 | 4-(trichloromethylthio) anilines, method for production thereof, and method for producing 4-(trifluoromethylthio) anilines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-03-19 | — | — | US | disclosed |
| US-8399707-B2 | 4-(trichloromethylthio) anilines, method for production thereof, and method for producing 4-(trifluoromethylthio) anilines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-03-19 | — | — | US | disclosed |
| US-8399707-B2 | 4-(trichloromethylthio) anilines, method for production thereof, and method for producing 4-(trifluoromethylthio) anilines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-03-19 | — | — | US | disclosed |
| US-20120245388-A1 | 4-(TRICHLOROMETHYLTHIO) ANILINES, METHOD FOR PRODUCTION THEREOF, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO) ANILINES | SUMITOMO CHEMICAL COMPANY, LIMITED | 2012-09-27 | — | — | US | disclosed |
| US-20120245388-A1 | 4-(TRICHLOROMETHYLTHIO) ANILINES, METHOD FOR PRODUCTION THEREOF, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO) ANILINES | SUMITOMO CHEMICAL COMPANY, LIMITED | 2012-09-27 | — | — | US | disclosed |
| US-20100331578-A1 | 4-(TRICHLOROMETHYLTHIO) ANILINES, METHOD FOR PRODUCTION THEREOF, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO) ANILINES | SUMITOMO CHEMICAL COMPANY, LIMITED | 2010-12-30 | — | — | US | disclosed |
| US-20100331578-A1 | 4-(TRICHLOROMETHYLTHIO) ANILINES, METHOD FOR PRODUCTION THEREOF, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO) ANILINES | SUMITOMO CHEMICAL COMPANY, LIMITED | 2010-12-30 | — | — | US | disclosed |
| US-20100331578-A1 | 4-(TRICHLOROMETHYLTHIO) ANILINES, METHOD FOR PRODUCTION THEREOF, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO) ANILINES | SUMITOMO CHEMICAL COMPANY, LIMITED | 2010-12-30 | — | — | US | disclosed |
| EP-2174929-A1 | 4-(TRICHLOROMETHYLTHIO)ANILINE, METHOD FOR PRODUCING THE SAME, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO)ANILINE | Sumitomo Chemical Company, Limited (JP) | 2010-04-14 | — | — | EP | disclosed |
| EP-2174929-A1 | 4-(TRICHLOROMETHYLTHIO)ANILINE, METHOD FOR PRODUCING THE SAME, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO)ANILINE | Sumitomo Chemical Company, Limited (JP) | 2010-04-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245388-A1 | 4-(TRICHLOROMETHYLTHIO) ANILINES, METHOD FOR PRODUCTION THEREOF, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO) ANILINES | PFAS, AFF4, ACSL4 | KCNK2 1820/4885KCNK10 3176/4885KIF11 1057/4885 |
| US-20100331578-A1 | 4-(TRICHLOROMETHYLTHIO) ANILINES, METHOD FOR PRODUCTION THEREOF, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO) ANILINES | PFAS, AFF4, ACSL4 | KCNK2 1820/4885KCNK10 3176/4885KIF11 1057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.