Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3551342 | 0.74 | SLC6A2 (0.52) | HTTSLC6A2NOTUMCDK4CCND1 | |
| SCHEMBL4065276 | 0.71 | HTR6 (0.61) | HTTMEN1HTR6KMT2AALDH1A1 | |
| SCHEMBL29558089 | 0.71 | HTR6 (0.61) | HTTMEN1HTR6KMT2AALDH1A1 | |
| SCHEMBL6623448 | 0.71 | SLC6A2 (0.49) | HTTSLC6A2KMT2ANOTUMCDK4 | |
| SCHEMBL10973432 | 0.70 | NOTUM (0.55) | HTTSLC6A2MEN1HTR6KMT2A | |
| SCHEMBL30371592 | 0.70 | NOTUM (0.55) | HTTSLC6A2MEN1HTR6KMT2A | |
| SCHEMBL6619810 | 0.70 | HTT (0.72) | HTTHTR6KMT2AALDH1A1LMNA | |
| SCHEMBL15707807 | 0.70 | SLC6A2 (0.52) | HTTSLC6A2MEN1HTR6KMT2A | |
| SCHEMBL10826333 | 0.70 | SLC6A2 (0.52) | HTTSLC6A2MEN1HTR6KMT2A | |
| SCHEMBL4108478 | 0.69 | CA12 (0.52) | HTTSLC6A2MEN1HTR6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12379315-B2 | Nitrodiarylethenes as fluorescence quenchers for nucleic acid probes | ELITECHGROUP MDX LLC (US) | 2025-08-05 | — | — | US | disclosed |
| EP-3247710-B1 | COUMARIN-BASED COMPOUNDS AND RELATED METHODS | BIOSEARCH TECH INC (US) | 2022-10-19 | — | — | EP | disclosed |
| US-20220119424-A1 | NITRODIARYLETHENES AS FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | ELITechGroup MDX, LLC (US) | 2022-04-21 | — | — | US | disclosed |
| US-11242554-B2 | Nitrodiarylethenes as fluorescence quenchers for nucleic acid probes | ELITECHGROUP, INC. (US) | 2022-02-08 | — | — | US | disclosed |
| US-11034677-B2 | Coumarin-based compounds and related methods | BIOSEARCH TECHNOLOGIES, INC. (US) | 2021-06-15 | — | — | US | disclosed |
| US-20200299755-A1 | NITRODIARYLETHENES AS FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | ELITECHGROUP, INC. (US) | 2020-09-24 | — | — | US | disclosed |
| US-10738346-B2 | Nitrodiarylethenes as fluorescence quenchers for nucleic acid probes | ELITECHGROUP, INC. (US) | 2020-08-11 | — | — | US | disclosed |
| WO-2018162986-A2 | NITRODIARYLETHENES AS FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | ELITECHGROUP B.V. (NL) | 2018-09-13 | — | — | WO | disclosed |
| US-20180258471-A1 | NITRODIARYLETHENES AS FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | ELITECHGROUP B.V. (NL) | 2018-09-13 | — | — | US | disclosed |
| EP-3247710-A1 | COUMARIN-BASED COMPOUNDS AND RELATED METHODS | Biosearch Technologies, Inc. (US) | 2017-11-29 | — | — | EP | disclosed |
| US-20170015652-A1 | Coumarin-based compounds and related methods | BIOSEARCH TECHNOLOGIES, INC. | 2017-01-19 | — | — | US | disclosed |
| WO-2016118305-A1 | COUMARIN-BASED COMPOUNDS AND RELATED METHODS | BIOSEARCH TECHNOLOGIES, INC. (US) | 2016-07-28 | — | — | WO | disclosed |
| EP-1842923-B1 | Methanesulfonylaminoindole derivatives and labeled oligonucleotide probes containing them | ROCHE DIAGNOSTICS GMBH (DE) | 2015-07-15 | — | — | EP | disclosed |
| EP-2142516-A1 | PYRIMIDINE HYDRAZIDE COMPOUNDS AS PGDS INHIBITORS | Sanofi-Aventis (FR) | 2010-01-13 | — | — | EP | disclosed |
| WO-2008121670-A1 | PYRIMIDINE HYDRAZIDE COMPOUNDS AS PGDS INHIBITORS | SANOFI-AVENTIS (FR) | 2008-10-09 | — | — | WO | disclosed |
| EP-1842923-A1 | Methanesulfonylaminoindole derivatives and labeled oligonucleotide probes containing them. | Roche Diagnostics GmbH (DE) | 2007-10-10 | — | — | EP | disclosed |
| EP-0733628-B9 | 5-Substituted-3-(1,2,3,6-tetrahydropyridin-4-yl)- and 3-(piperidin-4-yl)-1H-indoles: 5-HT1F agonists | LILLY CO ELI (US) | 2002-06-12 | — | — | EP | disclosed |
| EP-0733628-B1 | 5-Substituted-3-(1,2,3,6-tetrahydropyridin-4-yl)- and 3-(piperidin-4-yl)-1H-indoles: 5-HT1F agonists | LILLY CO ELI (US) | 2000-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220119424-A1 | NITRODIARYLETHENES AS FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | DNTT, NME2, DUT | HTT 783/4885SLC6A2 321/4885MEN1 3874/4885 |
| US-20200299755-A1 | NITRODIARYLETHENES AS FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | DNTT, NME2, DUT | HTT 783/4885SLC6A2 321/4885MEN1 3874/4885 |
| US-11034677-B2 | Coumarin-based compounds and related methods | HCCS, FBL, COIL | HTT 2440/4885SLC6A2 4536/4885MEN1 2472/4885 |
| US-10738346-B2 | Nitrodiarylethenes as fluorescence quenchers for nucleic acid probes | DNTT, NME2, DUT | HTT 783/4885SLC6A2 321/4885MEN1 3874/4885 |
| US-11242554-B2 | Nitrodiarylethenes as fluorescence quenchers for nucleic acid probes | DNTT, NME2, DUT | HTT 783/4885SLC6A2 321/4885MEN1 3874/4885 |
| US-20170015652-A1 | Coumarin-based compounds and related methods | HCCS, FBL, COIL | HTT 2440/4885SLC6A2 4536/4885MEN1 2472/4885 |
| US-12379315-B2 | Nitrodiarylethenes as fluorescence quenchers for nucleic acid probes | DNTT, NME2, DUT | HTT 783/4885SLC6A2 321/4885MEN1 3874/4885 |
| US-20180258471-A1 | NITRODIARYLETHENES AS FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | DNTT, NME2, DUT | HTT 783/4885SLC6A2 321/4885MEN1 3874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.