Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.65 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29666490 | 0.83 | SIGMAR1 (0.67) | SIGMAR1NR4A1NR4A2NR4A3GAA | |
| SCHEMBL1614544 | 0.83 | SIGMAR1 (0.67) | SIGMAR1NR4A1NR4A2NR4A3GAA | |
| SCHEMBL3626830 | 0.83 | SIGMAR1 (0.67) | SIGMAR1NR4A1NR4A2NR4A3GAA | |
| SCHEMBL11872011 | 0.81 | SIGMAR1 (0.65) | SIGMAR1NR4A1NR4A2NR4A3GAA | |
| SCHEMBL1839015 | 0.81 | SIGMAR1 (0.65) | SIGMAR1GAA | |
| SCHEMBL8150820 | 0.81 | SIGMAR1 (0.65) | SIGMAR1NR4A1NR4A2NR4A3GAA | |
| SCHEMBL28259034 | 0.81 | SIGMAR1 (0.65) | SIGMAR1NR4A1NR4A2NR4A3GAA | |
| SCHEMBL3069177 | 0.81 | SIGMAR1 (0.48) | SIGMAR1NR4A1NR4A2NR4A3GAA | |
| SCHEMBL28104518 | 0.80 | DHFR (0.43) | SIGMAR1 | |
| SCHEMBL6561817 | 0.79 | SIGMAR1 (0.61) | SIGMAR1NR4A1NR4A2NR4A3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4554015-A | THIOCARBAMATES | TOYO SODA MANUFACTURING CO., LTD. (JP) | 1985-11-19 | — | — | US | disclosed |