SCHEMBL3627353

SCHEMBL3627353

Clc1ccnc(-c2ncc[nH]2)c1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 2/20 0.42
MTOR P42345 1/20 0.42
ADK P55263 1/20 0.42
ALDH1A1 P00352 3/20 0.42
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
ADRA2A P08913 2/20 0.41
ADRA2C P18825 1/20 0.41
ADRA1D P25100 1/20 0.41
ADRA1A P35348 1/20 0.41
ADRA1B P35368 1/20 0.41
AXL P30530 1/20 0.40
PRKCI P41743 1/20 0.40
KDM4E B2RXH2 2/20 0.36
TAAR1 Q96RJ0 1/20 0.36
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 2/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
NPC1 O15118 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3625099 0.81 NISCH (0.40) NISCHMTORADKALDH1A1KMT2A
SCHEMBL6924805 0.77 ADRA2A (0.49) NISCHMTORADKALDH1A1KMT2A
SCHEMBL893307 0.72 ADRA1A (0.47) NISCHMTORADKALDH1A1KMT2A
SCHEMBL81650 0.68 NISCH (0.59) NISCHMTORADKALDH1A1KMT2A
SCHEMBL6002606 0.68 ADRA2A (0.52) NISCHMTORADKALDH1A1KMT2A
SCHEMBL27712534 0.68 NISCH (0.55) NISCHMTORADKALDH1A1KMT2A
SCHEMBL31627299 0.68 NISCH (0.41) NISCHMTORADKALDH1A1KMT2A
SCHEMBL11695206 0.67 CSNK1A1 (0.41) NISCHMTORADKALDH1A1KMT2A
SCHEMBL31595661 0.67 KMT2A (0.49) NISCHMTORADKALDH1A1KMT2A
SCHEMBL4637681 0.67 AXL (0.34) AXLPRKCI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2144898-A2 HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME Sumitomo Chemical Company, Limited (JP) 2010-01-20 EP disclosed
WO-2008130021-A2 HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-30 WO disclosed
EP-1937664-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME Sumitomo Chemical Company, Limited (JP) 2008-07-02 EP disclosed
WO-2007043677-A9 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2007-06-07 WO disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 WO disclosed