SCHEMBL893307

SCHEMBL893307

Clc1cccc(-c2ncc[nH]2)c1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA1A P35348 2/20 0.47
ADRA2A P08913 1/20 0.47
ADRA2C P18825 1/20 0.47
ADRA1D P25100 1/20 0.47
ADRA1B P35368 1/20 0.47
CSNK1A1 P48729 1/20 0.46
TYRO3 Q06418 1/20 0.46
DYRK1B Q9Y463 1/20 0.46
TAAR1 Q96RJ0 1/20 0.46
NISCH Q9Y2I1 2/20 0.46
MTOR P42345 1/20 0.46
ADK P55263 1/20 0.46
MC4R P32245 1/20 0.44
IDO1 P14902 2/20 0.42
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
F2RL1 P55085 3/20 0.40
CXCR2 P25025 1/20 0.39
NOTUM Q6P988 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1458606 0.85 NISCH (0.53) ADRA1AADRA2AADRA2CADRA1DADRA1B
SCHEMBL2053341 0.82 ADRA1A (0.45) ADRA1AADRA2AADRA2CADRA1DADRA1B
SCHEMBL11847005 0.82 NISCH (0.44) ADRA1AADRA2AADRA2CADRA1DADRA1B
SCHEMBL3670744 0.81 NISCH (0.50) ADRA1AADRA2AADRA2CADRA1DADRA1B
SCHEMBL6002606 0.79 ADRA2A (0.52) ADRA1AADRA2AADRA2CADRA1DADRA1B
SCHEMBL26259965 0.78 NISCH (0.54) ADRA1AADRA2AADRA2CADRA1DADRA1B
SCHEMBL9287236 0.78 NISCH (0.64) ADRA1AADRA2AADRA2CCSNK1A1TYRO3
SCHEMBL11695206 0.76 CSNK1A1 (0.41) ADRA1AADRA2AADRA2CADRA1DADRA1B
SCHEMBL28382846 0.76 CSNK1A1 (0.56) ADRA1AADRA2AADRA2CADRA1DADRA1B
Oxalic Acid SCHEMBL31679084 0.76 CSNK1A1 (0.56) ADRA1AADRA2AADRA2CADRA1DADRA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116925525-A Medical high-toughness waterproof breathable polyurethane film and preparation method thereof 江苏鑫易达新材料科技有限公司 2023-10-24 CN claimed
CN-112143079-B Antibacterial breathable film and preparation method thereof 福建琦峰科技有限公司 2023-07-11 CN claimed
CN-115054539-A Preparation process of gel for diminishing inflammation and removing scars 湖南科洛克医药有限公司 2022-09-16 CN claimed
CN-112064207-B Antibacterial deodorant spun-bonded non-woven fabric, planar mask with same and manufacturing method thereof 怡佳(福建)卫生用品股份有限公司 2022-07-01 CN claimed
CN-212862884-U Operation device for production of dichlorophenyl imidazole dioxolane 重庆美杉蓝科技发展有限公司 2021-04-02 CN claimed
CN-112064207-A Antibacterial deodorant spun-bonded non-woven fabric, planar mask with same and manufacturing method thereof 怡佳(福建)卫生用品有限公司 2020-12-11 CN claimed
CN-212102650-U Dichlorophenyl imidazole dioxolane production is with extracting jar 重庆美杉蓝科技发展有限公司 2020-12-08 CN claimed
CN-212031424-U Detection device is used in production of dichlorophenyl imidazole dioxolane 重庆美杉蓝科技发展有限公司 2020-11-27 CN claimed
US-20120082728-A1 MULTIFUNCTIONAL STEALTH NANOPARTICULES FOR BIOMEDICAL USE UNIVERSITE DE STRASBOURG (FR) 2012-04-05 US claimed
EP-2389199-A2 MULTIFUNCTIONAL STEALTH NANOPARTICLES FOR BIOMEDICAL USE THE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2011-11-30 EP claimed
WO-2010084157-A2 MULTIFUNCTIONAL STEALTH NANOPARTICLES FOR BIOMEDICAL USE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2010-07-29 WO claimed
EP-2210616-A1 Multifunctional stealth nanoparticles for biomedical use Centre National de la Recherche Scientifique (FR) 2010-07-28 EP claimed
EP-1900353-A1 Composition to combat localised hyperpigmentation in dark skin types L'OREAL (FR) 2008-03-19 EP claimed
WO-2002047652-A1 COMPOSITION CONTAINING 7-HYDROXY DHEA AND/OR 7-KETO DHEA AND AT LEAST AN ANTIMICROBIAL AGENT L'OREAL (FR) 2002-06-20 WO claimed
CN-122094562-A Synergistic preservative blend and composition containing the same 2026-05-26 CN disclosed
US-12629362-B2 Small molecule inhibitors of autophagy and histone deactylases and uses thereof ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2026-05-19 US disclosed
US-12569577-B2 PSMA-targeting imaging agents THE CLEVELAND CLINIC FOUNDATION (US) 2026-03-10 US disclosed
WO-2002094212-A1 COSMETIC USES OF 3-BETA-ACETOXY-7-OXO DHEA L'OREAL (FR) 2002-11-28 WO disclosed
WO-2002047652-A1 COMPOSITION CONTAINING 7-HYDROXY DHEA AND/OR 7-KETO DHEA AND AT LEAST AN ANTIMICROBIAL AGENT L'OREAL (FR) 2002-06-20 WO disclosed
CN-1283457-A Medicine for treating hircus LIU WENTONG (CN) 2001-02-14 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12629362-B2 Small molecule inhibitors of autophagy and histone deactylases and uses thereof HDAC3, HDAC4, HDAC5 ADRA1A 3431/4885ADRA2A 4208/4885ADRA2C 4161/4885
US-12569577-B2 PSMA-targeting imaging agents FOLH1, PSMA2, PSMA1 ADRA1A 1109/4885ADRA2A 1595/4885ADRA2C 1995/4885
US-20120082728-A1 MULTIFUNCTIONAL STEALTH NANOPARTICULES FOR BIOMEDICAL USE EPHA2, CD47, MSN ADRA1A 1105/4885ADRA2A 761/4885ADRA2C 1726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.