Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 6/20 | 0.50 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3627471 | 0.95 | ALDH1A3 (0.51) | ALDH1A3APPRAB9AKDM4ENPC1 | |
| SCHEMBL3301661 | 0.84 | APP (0.61) | ALDH1A3APPRAB9AKDM4ENPC1 | |
| SCHEMBL3629405 | 0.81 | ALDH1A3 (0.44) | ALDH1A3APPRAB9AKDM4ENPC1 | |
| SCHEMBL2817233 | 0.78 | APP (0.62) | ALDH1A3APPRAB9AKDM4ENPC1 | |
| SCHEMBL3624019 | 0.77 | ALDH1A3 (0.44) | ALDH1A3APPRAB9AKDM4ENPC1 | |
| SCHEMBL3629504 | 0.77 | APP (0.57) | ALDH1A3APPRAB9AKDM4ENPC1 | |
| SCHEMBL3625931 | 0.76 | RAB9A (0.57) | ALDH1A3APPRAB9AKDM4ENPC1 | |
| SCHEMBL1727344 | 0.75 | APP (0.62) | ALDH1A3APPRAB9AKDM4ENPC1 | |
| SCHEMBL12855179 | 0.74 | HRH3 (0.68) | ALDH1A3APPRAB9AKDM4ENPC1 | |
| SCHEMBL3302992 | 0.74 | HRH3 (0.53) | ALDH1A3APPRAB9AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399672-B2 | Compound having affinity for amyloid | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2013-03-19 | — | — | US | disclosed |
| US-20100292479-A1 | NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2010-11-18 | — | — | US | disclosed |
| EP-2213671-A1 | NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID | Nihon Medi-Physics Co., Ltd. (JP) | 2010-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292479-A1 | NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID | APP, APBA1, BACE1 | ALDH1A3 3022/4885APP 1/4885RAB9A 2413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.