Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.57 |
| ▸ | ALDH1A3 | P47895 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 9/20 | 0.53 |
| ▸ | PKM | P14618 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | GFER | P55789 | 3/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 9/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2817276 | 0.81 | ALDH1A3 (0.70) | APPALDH1A3NPC1PKMPOLB | |
| SCHEMBL2899627 | 0.81 | ALDH1A3 (0.70) | APPALDH1A3NPC1PKMPOLB | |
| Bromide SCHEMBL3300229 | 0.80 | ALDH1A3 (0.68) | APPALDH1A3NPC1PKMPOLB | |
| SCHEMBL3627471 | 0.78 | ALDH1A3 (0.51) | APPALDH1A3NPC1PKMPOLB | |
| SCHEMBL13325701 | 0.78 | ALDH1A3 (0.74) | APPALDH1A3NPC1PKMPOLB | |
| SCHEMBL3627422 | 0.77 | ALDH1A3 (0.50) | APPALDH1A3NPC1PKMPOLB | |
| SCHEMBL3628740 | 0.77 | RAB9A (0.57) | APPALDH1A3NPC1PKMPOLB | |
| Bromide SCHEMBL3629507 | 0.76 | RAB9A (0.57) | APPALDH1A3NPC1PKMPOLB | |
| SCHEMBL2901138 | 0.75 | ALDH1A3 (0.75) | APPALDH1A3NPC1PKMPOLB | |
| SCHEMBL2906109 | 0.75 | ALDH1A3 (0.70) | APPALDH1A3NPC1PKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399672-B2 | Compound having affinity for amyloid | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2013-03-19 | — | — | US | disclosed |
| US-20100292479-A1 | NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2010-11-18 | — | — | US | disclosed |
| EP-2213671-A1 | NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID | Nihon Medi-Physics Co., Ltd. (JP) | 2010-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292479-A1 | NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID | APP, APBA1, BACE1 | APP 1/4885ALDH1A3 3022/4885NPC1 948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.