Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 3/20 | 0.40 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 6/20 | 0.39 |
| ▸ | CA1 | P00915 | 6/20 | 0.39 |
| ▸ | CA2 | P00918 | 6/20 | 0.39 |
| ▸ | CA9 | Q16790 | 6/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.39 |
| ▸ | CA7 | P43166 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | CA3 | P07451 | 3/20 | 0.39 |
| ▸ | CA4 | P22748 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | MB | P02144 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL10441181 | 0.92 | ALDH1A1 (0.37) | NR1H2PREPCELA1CA12CA1 | |
| 1,3-Propanediol SCHEMBL10441202 | 0.89 | ALDH1A1 (0.35) | NR1H2PREPCELA1CA12CA1 | |
| 1,4-Butanediol SCHEMBL10441179 | 0.89 | ALDH1A1 (0.35) | NR1H2PREPCELA1CA12CA1 | |
| SCHEMBL21332455 | 0.83 | LMNA (0.48) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL21332520 | 0.81 | HSD17B10 (0.42) | MAPTALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL27727725 | 0.81 | SMN1; SMN2 (0.41) | CA1CA2MAPTALDH1A1MEN1 | |
| SCHEMBL27382881 | 0.81 | LMNA (0.40) | CA1CA2MAPTALDH1A1MEN1 | |
| SCHEMBL12473094 | 0.81 | CYP3A4 (0.41) | MAPTALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL5355354 | 0.80 | ALDH1A1 (0.45) | MAPTALDH1A1CYP3A4TSHRKDM4E | |
| SCHEMBL15654917 | 0.79 | MTNR1A (0.47) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161255-A1 | Phenolic Compound and Recording Material Using the Same | NIPPON SODA CO., LTD. (JP) | 2010-03-10 | — | — | EP | disclosed |
| EP-1768954-A4 | 2-METHYLPROPANAMIDES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2008-05-28 | — | — | EP | disclosed |
| EP-1768954-A2 | 2-METHYLPROPANAMIDES AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006002361-A2 | 2-METHYLPROPANAMIDES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-01-05 | — | — | WO | disclosed |
| EP-0056172-B1 | PHENOXY- AND THIOPHENOXY COMPOUNDS, METHODS FOR THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | FISONS plc (GB) | 1985-04-03 | — | — | EP | disclosed |
| EP-0056172-A2 | Phenoxy- and thiophenoxy compounds, methods for their preparation and pharmaceutical formulations containing them | FISONS plc (GB) | 1982-07-21 | — | — | EP | disclosed |