Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | ACR | P10323 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.40 |
| ▸ | SELE | P16581 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16628 | 0.89 | RAB9A (0.46) | HTTALDH1A1MAPTMEN1RAB9A | |
| SCHEMBL18614728 | 0.89 | RAB9A (0.46) | HTTALDH1A1MAPTMEN1RAB9A | |
| Methyl Alcohol SCHEMBL7601547 | 0.87 | RAB9A (0.44) | HTTALDH1A1MAPTMEN1RAB9A | |
| Isopropylbenzene SCHEMBL4795495 | 0.81 | MEN1 (0.46) | MAPTMEN1RAB9AKMT2A | |
| Acetone SCHEMBL11207944 | 0.81 | RAB9A (0.49) | ALDH1A1PRSS1ACRMAPTMEN1 | |
| Bicarbonate SCHEMBL11150406 | 0.81 | RAB9A (0.49) | MAPTMEN1RAB9AKMT2ACA12 | |
| Formaldehyde SCHEMBL8074512 | 0.81 | RAB9A (0.44) | HTTALDH1A1PRSS1ACRMAPT | |
| Tert-Butyl Hydroperoxide SCHEMBL4657003 | 0.79 | KMT2A (0.40) | HTTALDH1A1MEN1RAB9AKMT2A | |
| SCHEMBL8373970 | 0.78 | RAB9A (0.39) | HTTALDH1A1MAPTMEN1RAB9A | |
| Benzoquinone SCHEMBL5141654 | 0.78 | TYR (0.44) | ALDH1A1PRSS1ACRMAPTICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142163-B1 | SELF-ADHESIVE DENTAL CEMENT | DENTSPLY INT INC (US) | 2015-11-04 | — | — | EP | disclosed |
| US-8198343-B2 | Self-adhesive dental cement | DENTSPLY INTERNATIONAL INC. (US) | 2012-06-12 | — | — | US | disclosed |
| EP-2142163-A2 | SELF-ADHESIVE DENTAL CEMENT | Dentsply International Inc. (US) | 2010-01-13 | — | — | EP | disclosed |
| US-20090048364-A1 | Self-adhesive dental cement | LIU HUAIBING | 2009-02-19 | — | — | US | disclosed |
| WO-2008134024-A2 | SELF-ADHESIVE DENTAL CEMENT | DENTSPLY INTERNATIONAL INC. (US) | 2008-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048364-A1 | Self-adhesive dental cement | TBCA, HSPA4, HSPA4L | HTT 191/4885ALDH1A1 632/4885PRSS1 3472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.