Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3629396 | 0.75 | KDM4E (0.37) | ALDH1A1KDM4EGAAGABRA1GABRG2 | |
| SCHEMBL3629398 | 0.75 | KDM4E (0.37) | ALDH1A1KDM4EGAAGABRA1GABRG2 | |
| SCHEMBL3629402 | 0.75 | KDM4E (0.37) | ALDH1A1KDM4EGAAGABRA1GABRG2 | |
| SCHEMBL3632093 | 0.75 | LMNA (0.48) | ALDH1A1KDM4EGAANPC1MAPT | |
| SCHEMBL10041862 | 0.69 | MAPT (0.50) | ALDH1A1KDM4EGAAGABRA1GABRG2 | |
| SCHEMBL8220455 | 0.69 | MAPT (0.50) | ALDH1A1KDM4EGAAGABRA1GABRG2 | |
| SCHEMBL10905376 | 0.67 | KMT2A (0.55) | ALDH1A1KDM4EGAANPC1MAPT | |
| SCHEMBL10905375 | 0.67 | KMT2A (0.55) | ALDH1A1KDM4EGAANPC1MAPT | |
| SCHEMBL10905574 | 0.60 | KMT2A (0.46) | ALDH1A1KDM4ENPC1MAPTKMT2A | |
| SCHEMBL10905570 | 0.60 | KMT2A (0.46) | ALDH1A1KDM4ENPC1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142522-A1 | 1, 3-THIAZOL-2 (3H) -YLIDENE COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | Abbott Laboratories (US) | 2010-01-13 | — | — | EP | claimed |
| WO-2008121558-A1 | 1, 3-THIAZOL-2 (3H) -YLIDENE COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2008-10-09 | — | — | WO | claimed |