Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19378588 | 0.81 | LMNA (0.53) | LMNAKCNMA1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL3631756 | 0.78 | PTPN7 (0.40) | ALDH1A1L3MBTL1MAPTRAB9AKDM4E | |
| SCHEMBL3629922 | 0.78 | LMNA (0.46) | LMNAL3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL3629401 | 0.75 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1KMT2AMAPTNPC1 | |
| SCHEMBL3911579 | 0.74 | MAPT (0.52) | LMNAKCNMA1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL11306685 | 0.73 | LMNA (0.63) | LMNAKCNMA1ALDH1A1L3MBTL1MEN1 | |
| Iodide SCHEMBL6759686 | 0.72 | LMNA (0.50) | LMNAKCNMA1ALDH1A1L3MBTL1MEN1 | |
| Hydrochloric Acid SCHEMBL18920731 | 0.72 | MAPT (0.51) | LMNAKCNMA1ALDH1A1MEN1KMT2A | |
| SCHEMBL12127346 | 0.71 | LMNA (0.53) | LMNAKCNMA1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL16951330 | 0.71 | LMNA (0.56) | LMNAKCNMA1ALDH1A1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142522-A1 | 1, 3-THIAZOL-2 (3H) -YLIDENE COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | Abbott Laboratories (US) | 2010-01-13 | — | — | EP | claimed |
| WO-2008121558-A1 | 1, 3-THIAZOL-2 (3H) -YLIDENE COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2008-10-09 | — | — | WO | claimed |