Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | AKT2 | P31751 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | PDE2A | O00408 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL414533 | 1.00 | KCNN4 (0.55) | KCNN4TAAR1AKT1AKT2MAPK1 | |
| SCHEMBL6145 | 0.97 | KCNN4 (0.58) | KCNN4TAAR1AKT1AKT2MAPK1 | |
| Ammonia Solution, Strong SCHEMBL28009204 | 0.94 | KCNN4 (0.55) | KCNN4TAAR1AKT1AKT2MAPK1 | |
| Fluoride SCHEMBL634655 | 0.94 | KCNN4 (0.55) | KCNN4TAAR1AKT1AKT2MAPK1 | |
| Hydrochloric Acid SCHEMBL111457 | 0.94 | KCNN4 (0.55) | KCNN4TAAR1AKT1AKT2MAPK1 | |
| Hydrochloric Acid SCHEMBL8387827 | 0.94 | KCNN4 (0.55) | KCNN4TAAR1AKT1AKT2MAPK1 | |
| Iodide SCHEMBL6672017 | 0.94 | KCNN4 (0.55) | KCNN4TAAR1AKT1AKT2MAPK1 | |
| Water SCHEMBL4609376 | 0.94 | KCNN4 (0.55) | KCNN4TAAR1AKT1AKT2MAPK1 | |
| Methylamine SCHEMBL20916863 | 0.94 | KCNN4 (0.55) | KCNN4TAAR1AKT1AKT2MAPK1 | |
| Hydrochloric Acid SCHEMBL8388827 | 0.92 | KCNN4 (0.52) | KCNN4TAAR1AKT1AKT2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113150697-B | Polishing solution for monocrystalline silicon piece surface polishing and preparation method thereof | 广州凌玮科技股份有限公司 | 2023-08-22 | — | — | CN | claimed |
| CN-116583261-A | Method for combating microorganisms using menthol derivatives | 西姆莱斯股份公司 | 2023-08-11 | — | — | CN | claimed |
| CN-116120396-A | Polypeptide and application thereof in preparation of preservative | 华南协同创新研究院 | 2023-05-16 | — | — | CN | claimed |
| CN-114177341-B | Preparation method of antibacterial medical foam dressing | 常州美杰医疗用品有限公司 | 2023-01-31 | — | — | CN | claimed |
| CN-114177341-A | Preparation method of antibacterial medical foam dressing | 常州美杰医疗用品有限公司 | 2022-03-15 | — | — | CN | claimed |
| CN-111802404-A | Nano silver composite antibacterial and sterilizing material | 王一群 | 2020-10-23 | — | — | CN | claimed |
| CN-107892306-B | A kind of preparation method of low partial size high water absorption Silica Using for Toothpaste | 广州市飞雪材料科技有限公司 | 2019-11-15 | — | — | CN | claimed |
| CN-110144591-A | A kind of sea and is sealed up for safekeeping with preservative and its production method at the pressure testing of pipe pigging | 沈阳中科腐蚀控制工程技术中心 | 2019-08-20 | — | — | CN | claimed |
| CN-108148443-B | Preparation method of aqueous self-dispersion nano organic pigment powder | 江南大学 | 2019-08-20 | — | — | CN | claimed |
| CN-109782537-A | A kind of preparation method of high-precision semiconductor 3D printing formula negative photoresist | 中山职业技术学院 | 2019-05-21 | — | — | CN | claimed |
| CN-108148443-A | Preparation method of aqueous self-dispersion nano organic pigment powder | 江南大学 | 2018-06-12 | — | — | CN | claimed |
| CN-107892306-A | A kind of preparation method of low particle diameter high water absorption Silica Using for Toothpaste | 广州市飞雪材料科技有限公司 | 2018-04-10 | — | — | CN | claimed |
| CN-105903404-B | A kind of splashproof foaming agent based on Gemini quaternary ammonium salt surface active agents and preparation method thereof | 张放 | 2018-01-12 | — | — | CN | claimed |
| CN-107574006-A | A kind of optical glass grinding fluid and preparation method thereof | 广东星弛光电科技有限公司 | 2018-01-12 | — | — | CN | claimed |
| CN-104642385-B | The compound disinfectant and processing technology of a kind of Nanometer Copper and polyhexamethylene guanide | 安徽瀚驰生物科技有限公司 | 2017-08-25 | — | — | CN | claimed |
| CN-106867464-A | A kind of CNT composite aquogel based phase-change material and its preparation method and application | 江南大学 | 2017-06-20 | — | — | CN | claimed |
| CN-106556050-A | A kind of method of residual heat heating building system cleaning | 济南市琦泉热电有限责任公司 | 2017-04-05 | — | — | CN | claimed |
| CN-105903404-A | Splash-proof foam agent based on Gemini quaternary ammonium salt surfactant and preparation method for same | 张放 | 2016-08-31 | — | — | CN | claimed |
| CN-104487101-A | Compositions and methods for eradication of odors | NBIP LLC | 2015-04-01 | — | — | CN | claimed |
| EP-1937733-B1 | PROCESS FOR PREPARING AN AQUEOUS DISPERSION OF A QUATERNARY AMMONIUM SALT CONTAINING VINYL COPOLYMER | BOSTIK INC (US) | 2009-12-30 | — | — | EP | claimed |