Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 4/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | AKT2 | P31751 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | PDE2A | O00408 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6145 | 0.97 | KCNN4 (0.58) | KCNN4TAAR1AKT1AKT2MAPK1 | |
| Water SCHEMBL4609376 | 0.94 | KCNN4 (0.55) | KCNN4TAAR1AKT1AKT2MAPK1 | |
| Fluoride SCHEMBL634655 | 0.94 | KCNN4 (0.55) | KCNN4TAAR1AKT1AKT2MAPK1 | |
| Hydrochloric Acid SCHEMBL111457 | 0.94 | KCNN4 (0.55) | KCNN4TAAR1AKT1AKT2MAPK1 | |
| Bromide SCHEMBL414533 | 0.94 | KCNN4 (0.55) | KCNN4TAAR1AKT1AKT2MAPK1 | |
| Bromide SCHEMBL3629993 | 0.94 | KCNN4 (0.55) | KCNN4TAAR1AKT1AKT2MAPK1 | |
| Ammonia Solution, Strong SCHEMBL28009204 | 0.94 | KCNN4 (0.55) | KCNN4TAAR1AKT1AKT2MAPK1 | |
| Hydrochloric Acid SCHEMBL8387827 | 0.94 | KCNN4 (0.55) | KCNN4TAAR1AKT1AKT2MAPK1 | |
| Methylamine SCHEMBL20916863 | 0.94 | KCNN4 (0.55) | KCNN4TAAR1AKT1AKT2MAPK1 | |
| Hydrochloric Acid SCHEMBL8387706 | 0.92 | KCNN4 (0.52) | KCNN4TAAR1AKT1AKT2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026352-A1 | USE AS BINDER OF ION TRIGGERABLE, VINYL-BASED CATIONIC POLYMERS | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2004-04-01 | — | — | WO | claimed |