Fluoride

Fluoride

SCHEMBL634655

CC(C)(N)c1ccccc1.F

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 4/20 0.55
TAAR1 Q96RJ0 2/20 0.50
AKT1 P31749 1/20 0.50
AKT2 P31751 1/20 0.50
MAPK1 P28482 1/20 0.48
ALDH1A1 P00352 3/20 0.48
TSHR P16473 2/20 0.48
PDE2A O00408 1/20 0.46
MAPT P10636 1/20 0.46
KMT2A Q03164 1/20 0.46
ALOX15 P16050 1/20 0.44
SLC6A2 P23975 1/20 0.44
ESR1 P03372 2/20 0.42
ESR2 Q92731 2/20 0.42
CYP3A4 P08684 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL27345355 0.97 AKT1 (0.53) KCNN4TAAR1AKT1AKT2MAPK1
SCHEMBL6145 0.97 KCNN4 (0.58) KCNN4TAAR1AKT1AKT2MAPK1
Iodide SCHEMBL6672017 0.94 KCNN4 (0.55) KCNN4TAAR1AKT1AKT2MAPK1
Hydrochloric Acid SCHEMBL8387827 0.94 KCNN4 (0.55) KCNN4TAAR1AKT1AKT2MAPK1
Ammonia Solution, Strong SCHEMBL28009204 0.94 KCNN4 (0.55) KCNN4TAAR1AKT1AKT2MAPK1
Bromide SCHEMBL3629993 0.94 KCNN4 (0.55) KCNN4TAAR1AKT1AKT2MAPK1
Bromide SCHEMBL414533 0.94 KCNN4 (0.55) KCNN4TAAR1AKT1AKT2MAPK1
Water SCHEMBL4609376 0.94 KCNN4 (0.55) KCNN4TAAR1AKT1AKT2MAPK1
Methylamine SCHEMBL20916863 0.94 KCNN4 (0.55) KCNN4TAAR1AKT1AKT2MAPK1
Hydrochloric Acid SCHEMBL111457 0.94 KCNN4 (0.55) KCNN4TAAR1AKT1AKT2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2302000-B1 CURABLE COMPOSITION AND CATALYST COMPOSITION KANEKA CORP (JP) 2016-11-16 EP disclosed
US-9051501-B2 Curable composition and catalyst composition KANEKA CORPORATION (JP) 2015-06-09 US disclosed
EP-2088173-B1 CURABLE COMPOSITION AND CATALYST COMPOSITION KANEKA CORP (JP) 2012-02-22 EP disclosed
EP-2302000-A1 Curable composition and catalyst composition KANEKA CORPORATION (JP) 2011-03-30 EP disclosed
US-20100041810-A1 CURABLE COMPOSITION AND CATALYST COMPOSITION KANEKA CORPORATION (JP) 2010-02-18 US disclosed
EP-2088173-A1 CURABLE COMPOSITION AND CATALYST COMPOSITION Kaneka Corporation (JP) 2009-08-12 EP disclosed