Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363026 | 0.79 | KMO (0.59) | KMOMKNK1MKNK2TP53SMN1; SMN2 | |
| SCHEMBL27605054 | 0.77 | KMO (0.49) | KMOMKNK1MKNK2TP53SMN1; SMN2 | |
| SCHEMBL2724814 | 0.75 | ALDH1A1 (0.51) | KMOMKNK1MKNK2NPC1RAB9A | |
| SCHEMBL369291 | 0.74 | SCD (0.49) | KMOMKNK1MKNK2NPC1TP53 | |
| SCHEMBL364613 | 0.74 | CYP2A6 (0.51) | KMOMKNK1MKNK2NPC1RAB9A | |
| SCHEMBL21249399 | 0.73 | CYP19A1 (0.51) | MKNK1MKNK2NPC1TP53RAB9A | |
| SCHEMBL876393 | 0.72 | KMT2A (0.56) | ALDH1A1MAPTMAPK1 | |
| SCHEMBL31123876 | 0.72 | KMT2A (0.56) | ALDH1A1MAPTMAPK1 | |
| SCHEMBL6194452 | 0.71 | CYP3A4 (0.55) | TP53SMN1; SMN2ALDH1A1CYP1A2MAPT | |
| SCHEMBL15219313 | 0.70 | CYP2A6 (0.49) | NPC1TP53RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593447-B1 | 3-PYRIDYL-HETEROARYLCARBOXAMIDE COMPOUNDS AS PESTICIDES | BAYER IP GMBH (DE) | 2016-08-17 | — | — | EP | disclosed |
| EP-2593447-A2 | NEW HETEROCYCLIC COMPOUNDS AS PESTICIDES | Bayer Intellectual Property GmbH (DE) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007500-A2 | NEW HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2012-01-19 | — | — | WO | disclosed |