Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 10/20 | 0.50 |
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.43 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | SUV39H2 | Q9H5I1 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3627420 | 0.94 | TLR9 (0.54) | TLR9TLR7ALDH1A3TLR8SUV39H2 | |
| SCHEMBL3628363 | 0.79 | TLR9 (0.49) | TLR9TLR7ALDH1A3TLR8SUV39H2 | |
| SCHEMBL3629663 | 0.75 | TLR9 (0.44) | TLR9TLR7ALDH1A3TLR8KDM4E | |
| SCHEMBL1726360 | 0.74 | APP (0.56) | ALDH1A3APPKDM4ENPC1ALDH1A1 | |
| SCHEMBL1727248 | 0.73 | RAB9A (0.48) | ALDH1A3MAPTAPPKDM4ENPC1 | |
| SCHEMBL1728195 | 0.70 | APP (0.53) | ALDH1A3APPKDM4ENPC1ALDH1A1 | |
| SCHEMBL20445927 | 0.70 | SUV39H2 (0.65) | SUV39H2 | |
| SCHEMBL3625931 | 0.70 | RAB9A (0.57) | ALDH1A3MAPTAPPKDM4ENPC1 | |
| SCHEMBL796015 | 0.69 | APP (0.59) | ALDH1A3APPKDM4ENPC1ALDH1A1 | |
| SCHEMBL1472692 | 0.67 | CYP2C9 (0.59) | TLR9TLR7ALDH1A3TLR8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2213671-A1 | NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID | Nihon Medi-Physics Co., Ltd. (JP) | 2010-08-04 | — | — | EP | disclosed |