Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 8/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727327 | 0.84 | HRH3 (0.57) | HRH3ALDH1A3KDM4ENPC1ALDH1A1 | |
| SCHEMBL1727121 | 0.83 | ALDH1A1 (0.44) | HRH3ALDH1A3TLR8KDM4ENPC1 | |
| SCHEMBL1726366 | 0.81 | HRH3 (0.56) | HRH3ALDH1A3KDM4ENPC1ALDH1A1 | |
| SCHEMBL3627420 | 0.80 | TLR9 (0.54) | TLR9TLR7ALDH1A3TLR8DRD2 | |
| SCHEMBL1726212 | 0.79 | HRH3 (0.56) | HRH3ALDH1A3KDM4ENPC1ALDH1A1 | |
| SCHEMBL3622542 | 0.79 | RAB9A (0.49) | HRH3ALDH1A3KDM4ENPC1ALDH1A1 | |
| SCHEMBL2904661 | 0.78 | ALDH1A3 (0.60) | TLR9HRH3TLR7ALDH1A3TLR8 | |
| SCHEMBL1727498 | 0.75 | HRH3 (0.56) | HRH3KDM4ENPC1ALDH1A1PKM | |
| SCHEMBL3630481 | 0.75 | TLR9 (0.50) | TLR9TLR7ALDH1A3TLR8KDM4E | |
| SCHEMBL1726214 | 0.75 | RAB9A (0.56) | HRH3ALDH1A3KDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399672-B2 | Compound having affinity for amyloid | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2013-03-19 | — | — | US | disclosed |
| US-20100292479-A1 | NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2010-11-18 | — | — | US | disclosed |
| EP-2213671-A1 | NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID | Nihon Medi-Physics Co., Ltd. (JP) | 2010-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292479-A1 | NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID | APP, APBA1, BACE1 | TLR9 4842/4885HRH3 12/4885TLR7 4712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.