Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.40 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | PRCP | P42785 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL362904 | 0.91 | TLR8 (0.39) | ALDH1A1TLR8TLR7PROKR1POLB | |
| SCHEMBL364421 | 0.85 | PROKR1 (0.38) | TLR8TLR7PROKR1IDO1 | |
| SCHEMBL364904 | 0.81 | TLR8 (0.38) | ALDH1A1TLR8TLR7PROKR1POLB | |
| SCHEMBL363457 | 0.80 | CCR9 (0.38) | PROKR1 | |
| SCHEMBL362157 | 0.79 | PROKR1 (0.34) | TLR8TLR7PROKR1 | |
| SCHEMBL362899 | 0.79 | TLR8 (0.40) | TLR8TLR7PROKR1TP53KMT2A | |
| SCHEMBL364634 | 0.78 | PROKR1 (0.35) | PROKR1POLBSMN1; SMN2IDO1L3MBTL1 | |
| SCHEMBL362712 | 0.77 | SORT1 (0.34) | ALDH1A1PROKR1IDO1L3MBTL1 | |
| SCHEMBL364587 | 0.77 | SORT1 (0.34) | ALDH1A1PROKR1IDO1L3MBTL1 | |
| SCHEMBL363084 | 0.77 | SORT1 (0.34) | ALDH1A1PROKR1IDO1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |