Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2795948 | 0.88 | SIGMAR1 (0.74) | SIGMAR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL8092326 | 0.88 | SIGMAR1 (0.74) | SIGMAR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL719011 | 0.88 | SIGMAR1 (0.74) | SIGMAR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL593666 | 0.88 | SIGMAR1 (0.74) | SIGMAR1MEN1KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL1134234 | 0.87 | SIGMAR1 (0.72) | SIGMAR1MEN1KMT2AL3MBTL1MAPK1 | |
| Hydrochloric Acid SCHEMBL1134233 | 0.87 | SIGMAR1 (0.72) | SIGMAR1MEN1KMT2AL3MBTL1MAPK1 | |
| SCHEMBL3346880 | 0.86 | SIGMAR1 (0.62) | SIGMAR1NPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL3341840 | 0.86 | SIGMAR1 (0.62) | SIGMAR1NPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL3341844 | 0.86 | SIGMAR1 (0.62) | SIGMAR1NPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL6185283 | 0.85 | SIGMAR1 (0.60) | SIGMAR1NPC1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010128355-A2 | IMPROVED PROCESSES FOR PREPARING SUBSTANTIALLY PURE ARFORMOTEROL AND ITS INTERMEDIATES | ACTAVIS GROUP PTC EHF (IS) | 2010-11-11 | — | — | WO | disclosed |