SCHEMBL4411249

SCHEMBL4411249

NNC(=O)CCn1cccc1

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.51
HPGD P15428 2/20 0.51
KMT2A Q03164 7/20 0.47
MEN1 O00255 6/20 0.47
MAPT P10636 1/20 0.47
HTT P42858 1/20 0.45
HSD17B10 Q99714 1/20 0.45
POLB P06746 1/20 0.43
CTSD P07339 1/20 0.43
KDM4E B2RXH2 1/20 0.43
KDM5C P41229 1/20 0.43
PHF8 Q9UPP1 1/20 0.43
KDM2A Q9Y2K7 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18839708 0.77 HPGD (0.48) TSHRHPGDMAPTHTTKDM4E
SCHEMBL14967735 0.75 THRB (0.51) KMT2AMAPTPOLBCTSDKDM4E
SCHEMBL4415625 0.75 EGLN3 (0.62)
SCHEMBL6333046 0.75 LMNA (0.44) TSHRHPGDKMT2AMEN1HTT
SCHEMBL3631111 0.72 TSHR (0.55) TSHRHPGDKMT2AMEN1HTT
SCHEMBL4415628 0.71 MAPT (0.44) KMT2AMAPTHTTPOLBCTSD
SCHEMBL13296619 0.70 TSHR (0.43) TSHRHPGDKMT2AMEN1HTT
SCHEMBL7225425 0.70 TSHR (0.43) TSHRHPGDKMT2AMEN1HTT
SCHEMBL13712850 0.70 TSHR (0.52) TSHRHPGDKMT2AMEN1HTT
SCHEMBL8045914 0.70 TSHR (0.50) TSHRHPGDKMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100587001-C Polyacetal resin composition POLYPLASTICS CO 2010-02-03 CN disclosed
US-7638565-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-12-29 US disclosed
US-20070054998-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2007-03-08 US disclosed
CN-1878834-A Polyacetal resin composition POLYPLASTICS CO (JP) 2006-12-13 CN disclosed
EP-1686156-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-08-02 EP disclosed