Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21243278 | 0.82 | SIGMAR1 (0.42) | SIGMAR1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL794607 | 0.79 | SIGMAR1 (0.41) | SIGMAR1TSHR | |
| SCHEMBL3275777 | 0.74 | LTA4H (0.46) | SIGMAR1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL10512424 | 0.72 | MEN1 (0.46) | SIGMAR1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL8726699 | 0.70 | EPHX1 (0.50) | SIGMAR1LTA4H | |
| SCHEMBL8072690 | 0.70 | LTA4H (0.42) | SIGMAR1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7759621 | 0.70 | CSNK1E (0.47) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3270666 | 0.70 | CSNK1E (0.46) | SIGMAR1ALDH1A1HPGDLTA4HTSHR | |
| SCHEMBL6636645 | 0.70 | CSNK1E (0.44) | SIGMAR1 | |
| SCHEMBL7924701 | 0.69 | ALDH1A1 (0.41) | SIGMAR1ALDH1A1HPGDLTA4HTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2148853-A1 | INSECTICIDAL ARYL PYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2010-02-03 | — | — | EP | disclosed |
| WO-2008128711-A1 | INSECTICIDAL ARYL PYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2008-10-30 | — | — | WO | disclosed |