Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 16/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3631407 | 0.94 | FFAR1 (0.61) | FFAR1DRD4ADRA1DDRD3FFAR4 | |
| SCHEMBL3633081 | 0.90 | FFAR1 (0.60) | FFAR1DRD4ADRA1DDRD3FFAR4 | |
| SCHEMBL13226536 | 0.87 | FFAR1 (0.72) | FFAR1DRD4ADRA1DDRD3FFAR4 | |
| SCHEMBL3629803 | 0.86 | FFAR1 (0.55) | FFAR1FFAR4 | |
| SCHEMBL3633078 | 0.84 | FFAR1 (0.68) | FFAR1DRD4ADRA1DDRD3FFAR4 | |
| SCHEMBL3631602 | 0.83 | FFAR1 (0.61) | FFAR1FFAR4 | |
| SCHEMBL3629804 | 0.82 | FFAR1 (0.62) | FFAR1FFAR4 | |
| SCHEMBL3631721 | 0.78 | FFAR1 (0.44) | FFAR1FFAR4P2RX3 | |
| SCHEMBL3633076 | 0.78 | FFAR1 (0.65) | FFAR1FFAR4 | |
| SCHEMBL3631605 | 0.78 | FFAR1 (0.35) | FFAR1DRD4ADRA1DDRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7786165-B2 | Aminophenylpropanoic acid derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-31 | — | — | US | disclosed |
| US-20080269220-A1 | Aminophenylpropanoic Acid Derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-10-30 | — | — | US | disclosed |
| EP-1726580-A1 | AMINOPHENYLPROPANOIC ACID DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2006-11-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269220-A1 | Aminophenylpropanoic Acid Derivative | GPR119, GPR55, GPR65 | FFAR1 5/4885DRD4 2571/4885ADRA1D 67/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.