Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 6/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL15414575 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL43479 | 0.88 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL9152986 | 0.82 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL1004629 | 0.82 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL11375032 | 0.82 | — | — | |
| Bicarbonate SCHEMBL1259818 | 0.82 | — | — | |
| Bicarbonate SCHEMBL6260807 | 0.82 | — | — | |
| Bicarbonate SCHEMBL344377 | 0.82 | — | — | |
| Bicarbonate SCHEMBL15104745 | 0.82 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL5359205 | 0.82 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2158289-B1 | METHODS FOR STIMULATING OIL OR GAS PRODUCTION | HALLIBURTON ENERGY SERVICES INC (US) | 2016-12-07 | — | — | EP | disclosed |
| EP-2548934-A1 | Methods for stimulating oil or gas production | Halliburton Energy Services, Inc. (US) | 2013-01-23 | — | — | EP | disclosed |
| US-20130000902-A1 | Methods for Stimulating Oil or Gas Production Using a Viscosified Aqueous Fluid with a Chelating Agent to Remove Calcium Carbonate and Similar Materials from the Matrix of a Formation or a Proppant Pack | HALLIBURTON ENERGY SERVICES, INC. (US) | 2013-01-03 | — | — | US | disclosed |
| US-20130000901-A1 | Methods for Stimulating Oil or Gas Production Using a Viscosified Aqueous Fluid with a Chelating Agent to Remove Calcium Carbonate and Similar Materials from the Matrix of a Formation or a Proppant Pack | HALLIBURTON ENERGY SERVICES, INC. (US) | 2013-01-03 | — | — | US | disclosed |
| US-20130000913-A1 | Methods for Stimulating Oil or Gas Production Using a Viscosified Aqueous Fluid with a Chelating Agent to Remove Calcium Carbonate and Similar Materials from the Matrix of a Formation or a Proppant Pack | HALIBURTON ENERGY SERVICES, INC. (US) | 2013-01-03 | — | — | US | disclosed |
| US-20120186811-A1 | METHODS FOR STIMULATING OIL OR GAS PRODUCTION USING A VISCOSIFIED AQUEOUS FLUID WITH A CHELATING AGENT TO REMOVE CALCIUM CARBONATE AND SIMILAR MATERIALS FROM THE MATRIX OF A FORMATION OR A PROPPANT PACK | HALLIBURTON ENERGY SERVICES, INC. (US) | 2012-07-26 | — | — | US | disclosed |
| EP-2158289-A1 | METHODS FOR STIMULATING OIL OR GAS PRODUCTION | Halliburton Energy Services, Inc. (US) | 2010-03-03 | — | — | EP | disclosed |
| WO-2008139164-A1 | METHODS FOR STIMULATING OIL OR GAS PRODUCTION | HALLIBURTON ENERGY SERVICES, INC. (US) | 2008-11-20 | — | — | WO | disclosed |
| US-20080280789-A1 | Methods for stimulating oil or gas production using a viscosified aqueous fluid with a chelating agent to remove scale from wellbore tubulars or subsurface equipment | HALLIBURTON ENERGY SERVICES, INC. | 2008-11-13 | — | — | US | disclosed |
| US-20080277112-A1 | Methods for stimulating oil or gas production using a viscosified aqueous fluid with a chelating agent to remove calcium carbonate and similar materials from the matrix of a formation or a proppant pack | HALLIBURTON ENERGY SERVICES, INC. | 2008-11-13 | — | — | US | disclosed |