Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | EYA2 | O00167 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27932229 | 0.87 | LMNA (0.42) | LMNAALDH1A1ALDH2CA12CA1 | |
| SCHEMBL17666073 | 0.81 | LMNA (0.33) | LMNAALDH1A1ALDH2MMP1MMP2 | |
| SCHEMBL7600779 | 0.75 | EGFR (0.32) | — | |
| SCHEMBL8891629 | 0.72 | LMNA (0.40) | LMNAALDH1A1ALDH2CA12CA1 | |
| SCHEMBL3714284 | 0.70 | LMNA (0.39) | LMNAALDH1A1ALDH2CA12CA1 | |
| SCHEMBL5532782 | 0.69 | LMNA (0.37) | LMNAALDH1A1ALDH2CA12CA1 | |
| SCHEMBL7547953 | 0.69 | ALDH1A1 (0.45) | LMNAALDH1A1ALDH2CA12CA1 | |
| SCHEMBL20849668 | 0.69 | LMNA (0.37) | LMNAALDH1A1CA12CA1CA9 | |
| SCHEMBL13322397 | 0.69 | TDP1 (0.36) | LMNATDP1EYA2APPACE | |
| SCHEMBL8018156 | 0.68 | PSMB5 (0.40) | LMNAALDH1A1ALDH2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152405-A1 | GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY | Merck Patent GmbH (DE) | 2010-02-17 | — | — | EP | claimed |
| WO-2008145270-A1 | GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY | MERCK PATENT GMBH (DE) | 2008-12-04 | — | — | WO | claimed |