Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146928 | 0.89 | TSHR (0.53) | ACHETSHRALDH1A1CA1CA2 | |
| Hydrochloric Acid SCHEMBL541709 | 0.87 | TSHR (0.50) | ACHETSHRALDH1A1CA1CA2 | |
| SCHEMBL29083664 | 0.87 | TSHR (0.50) | ACHETSHRALDH1A1CA1CA2 | |
| SCHEMBL1304780 | 0.87 | TSHR (0.50) | ACHETSHRALDH1A1CA1CA2 | |
| SCHEMBL5645150 | 0.87 | TSHR (0.50) | ACHETSHRALDH1A1CA1CA2 | |
| SCHEMBL31457202 | 0.87 | TSHR (0.50) | ACHETSHRALDH1A1CA1CA2 | |
| SCHEMBL5138180 | 0.87 | CYP2A6 (0.41) | ACHETSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14604156 | 0.84 | APP (0.43) | SMN1; SMN2ALDH1A1CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL3223494 | 0.84 | TSHR (0.47) | ACHETSHRALDH1A1CA1CA2 | |
| Hydrochloric Acid SCHEMBL29042332 | 0.84 | TSHR (0.47) | ACHETSHRALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754924-B2 | Process for the monosulfonation of aromatic phosphines, and zwitterionic product derived therefrom | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-07-13 | — | — | US | disclosed |
| US-20080221363-A1 | Process for the Monosulfonation of Aromatic Phosphines, and Zwitterionic Product Derived Therefrom | DOW GLOBAL TECHNOLOGIES INC. (US) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221363-A1 | Process for the Monosulfonation of Aromatic Phosphines, and Zwitterionic Product Derived Therefrom | ITK, WEE1, WASF2 | ACHE 3112/4885TSHR 3802/4885NPC1 4654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.