SCHEMBL146928

SCHEMBL146928

Cc1ccccc1Pc1ccccc1C

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.53
ACHE P22303 3/20 0.53
ALDH1A1 P00352 4/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA7 P43166 2/20 0.41
CA9 Q16790 2/20 0.41
CYP3A4 P08684 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP1A2 P05177 2/20 0.38
CYP2A6 P11509 2/20 0.38
LMNA P02545 1/20 0.35
ALOX12 P18054 1/20 0.35
MAPT P10636 2/20 0.35
HTT P42858 1/20 0.35
ESR1 P03372 1/20 0.35
TAAR1 Q96RJ0 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL541709 0.97 TSHR (0.50) TSHRACHEALDH1A1CA1CA2
SCHEMBL1304780 0.97 TSHR (0.50) TSHRACHEALDH1A1CA1CA2
SCHEMBL31457202 0.97 TSHR (0.50) TSHRACHEALDH1A1CA1CA2
SCHEMBL29083664 0.97 TSHR (0.50) TSHRACHEALDH1A1CA1CA2
SCHEMBL5645150 0.97 TSHR (0.50) TSHRACHEALDH1A1CA1CA2
Hydrochloric Acid SCHEMBL29042332 0.94 TSHR (0.47) TSHRACHEALDH1A1CA1CA2
Hydrochloric Acid SCHEMBL3223494 0.94 TSHR (0.47) TSHRACHEALDH1A1CA1CA2
Bromide SCHEMBL29042359 0.94 TSHR (0.47) TSHRACHEALDH1A1CA1CA2
Propane SCHEMBL29069359 0.92 TSHR (0.45) TSHRACHEALDH1A1CA1CA2
SCHEMBL3632065 0.89 ACHE (0.43) TSHRACHEALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 441 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120157864-A Multi-center metalloporphyrin complex and application thereof in preparing polycarbonate through catalysis 烟台大学 2025-06-17 CN claimed
US-12162829-B2 Gas phase process for acrylate production from ethylene and carbon dioxide CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2024-12-10 US claimed
CN-118598834-A High-efficiency synthesis method of tetracyclic fused benzopyran 江苏海洋大学 2024-09-06 CN claimed
CN-116813528-A Synthesis method of all-carbon quaternary carbon cyclic ketone spiro indolenine derivative 江苏海洋大学 2023-09-29 CN claimed
CN-116730905-A Method for synthesizing carbonyl-containing all-carbon quaternary carbon spiro indolenine 江苏海洋大学 2023-09-12 CN claimed
CN-113072691-B Polycyclohexene carbonate copolymer and preparation method thereof 上海华峰新材料研发科技有限公司 2023-08-01 CN claimed
CN-114957674-B Organosilicon polyol and preparation method thereof 烟台大学 2023-06-23 CN claimed
US-20230192586-A1 GAS PHASE PROCESS FOR ACRYLATE PRODUCTION FROM ETHYLENE AND CARBON DIOXIDE CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2023-06-22 US claimed
WO-2023114926-A1 GAS PHASE PROCESS FOR ACRYLATE PRODUCTION FROM ETHYLENE AND CARBON DIOXIDE CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2023-06-22 WO claimed
US-11530177-B2 Formation of α,β-unsaturated carboxylic acids and salts thereof from metalalactones and anionic polyelectrolytes CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2022-12-20 US claimed
US-20210179525-A1 FORMATION OF ALPHA,BETA-UNSATURATED CARBOXYLIC ACIDS AND SALTS THEREOF FROM METALALACTONES AND ANIONIC POLYELECTROLYTES CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2021-06-17 US claimed
US-10941101-B2 Formation of alpha,beta-unsaturated carboxylic acids and salts thereof from metalalactones and anionic polyelectrolytes CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2021-03-09 US claimed
CN-108031493-B Catalyst system for selective oligomerization of ethylene and ethylene oligomerization reaction method 天津科技大学 2020-11-06 CN claimed
US-20190345089-A1 FORMATION OF ALPHA,BETA-UNSATURATED CARBOXYLIC ACIDS AND SALTS THEREOF FROM METALALACTONES AND ANIONIC POLYELECTROLYTES CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2019-11-14 US claimed
EP-1598053-B1 Use of a composition containing at least one phosphine as majority reducing agent to remove the artificial colour of keratinic fibres OREAL (FR) 2006-12-20 EP claimed
EP-1598053-A1 Use of a composition containing at least one phosphine as majority reducing agent to remove the artificial colour of keratinic fibres L'OREAL (FR) 2005-11-23 EP claimed
US-20050251928-A1 Method for stripping artificial color from keratin fibers L'OREAL (FR) 2005-11-17 US claimed
US-6583312-B2 Catalytic hydrogenation of trimethylpyruvic acid BAYER AKTIENGESELLSCHAFT (DE) 2003-06-24 US claimed
US-20020035271-A1 Process for preparing oprtically active trimethyllactic acid and its ester BAYER AKTIENGESELLSCHAFT (DE) 2002-03-21 US claimed
EP-1160237-A2 Method for the preparation of optically active trimethyllactic acid and its esters BAYER AG (DE) 2001-12-05 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190345089-A1 FORMATION OF ALPHA,BETA-UNSATURATED CARBOXYLIC ACIDS AND SALTS THEREOF FROM METALALACTONES AND ANIONIC POLYELECTROLYTES ALOX12, ME1, RARA TSHR 4722/4885ACHE 2534/4885ALDH1A1 338/4885
US-12162829-B2 Gas phase process for acrylate production from ethylene and carbon dioxide MSMO1, ALOX15, ALOX12 TSHR 3699/4885ACHE 406/4885ALDH1A1 1885/4885
US-10941101-B2 Formation of alpha,beta-unsaturated carboxylic acids and salts thereof from metalalactones and anionic polyelectrolytes ALOX12, ME1, RARA TSHR 4722/4885ACHE 2534/4885ALDH1A1 338/4885
US-20210179525-A1 FORMATION OF ALPHA,BETA-UNSATURATED CARBOXYLIC ACIDS AND SALTS THEREOF FROM METALALACTONES AND ANIONIC POLYELECTROLYTES ME1, DEGS1, ACSL1 TSHR 4680/4885ACHE 2150/4885ALDH1A1 353/4885
US-11530177-B2 Formation of α,β-unsaturated carboxylic acids and salts thereof from metalalactones and anionic polyelectrolytes ME1, ACSL1, ALOX12 TSHR 4661/4885ACHE 2310/4885ALDH1A1 344/4885
US-20230192586-A1 GAS PHASE PROCESS FOR ACRYLATE PRODUCTION FROM ETHYLENE AND CARBON DIOXIDE MSMO1, ALOX15, ALOX12 TSHR 3699/4885ACHE 406/4885ALDH1A1 1885/4885
US-20020035271-A1 Process for preparing oprtically active trimethyllactic acid and its ester ME1, OPRK1, OPRM1 TSHR 3279/4885ACHE 670/4885ALDH1A1 2551/4885
US-20050251928-A1 Method for stripping artificial color from keratin fibers KRT18, DSG1, JUP TSHR 4245/4885ACHE 704/4885ALDH1A1 4512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.