Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | NQO2 | P16083 | 6/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31039239 | 0.94 | KDM4E (0.51) | KDM4ENQO2ABL1ACHEPOLB | |
| SCHEMBL535539 | 0.94 | KDM4E (0.51) | KDM4ENQO2ABL1ACHEPOLB | |
| SCHEMBL535611 | 0.89 | KDM4E (0.47) | KDM4EGAASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL110643 | 0.80 | KDM4E (0.53) | KDM4ENQO2ABL1ACHEPOLB | |
| SCHEMBL29678780 | 0.80 | KDM4E (0.53) | KDM4ENQO2ABL1ACHEPOLB | |
| SCHEMBL31310191 | 0.78 | KDM4E (0.56) | KDM4ENQO2ACHEPOLBGAA | |
| SCHEMBL536169 | 0.77 | KDM4E (0.50) | KDM4ENQO2ABL1POLBGAA | |
| SCHEMBL30657473 | 0.77 | KDM4E (0.50) | KDM4ENQO2ABL1ACHEPOLB | |
| SCHEMBL26639879 | 0.77 | KDM4E (0.50) | KDM4ENQO2ABL1ACHEPOLB | |
| SCHEMBL17979068 | 0.77 | KDM4E (0.50) | KDM4ENQO2ABL1ACHEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144898-A2 | HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | Sumitomo Chemical Company, Limited (JP) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008130021-A2 | HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-10-30 | — | — | WO | disclosed |