Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 6/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | FCER2 | P06734 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11196457 | 0.98 | KIF11 (0.40) | KIF11SLC1A1CYP1A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL10770246 | 0.98 | KIF11 (0.40) | KIF11SLC1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16847765 | 0.86 | KIF11 (0.39) | KIF11TLR2TSHRHSD17B10 | |
| SCHEMBL3685147 | 0.85 | SLC1A1 (0.46) | KIF11SLC1A1 | |
| SCHEMBL3685144 | 0.85 | SLC1A1 (0.46) | KIF11SLC1A1 | |
| SCHEMBL22661903 | 0.85 | BHMT (0.42) | KIF11SLC1A1CYP1A2CYP2C9TLR2 | |
| Lysine SCHEMBL27653683 | 0.83 | GSR (0.53) | KIF11SLC1A1CYP1A2TLR2TSHR | |
| SCHEMBL23129041 | 0.80 | KIF11 (0.40) | KIF11TLR2 | |
| SCHEMBL1709969 | 0.80 | KIF11 (0.40) | KIF11TLR2 | |
| SCHEMBL27653685 | 0.80 | GSR (0.49) | SLC1A1TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0144519-B1 | 2',4'-DIFLUORO-4-HYDROXY-(1,1'-DIPHENYL)-3-CARBOXYLIC DERIVATIVES OF N-ACETYLCYSTEINE AND OF S-CARBOXYMETHYLCYSTEINE HAVING ANTI-INFLAMMATORY AND MUCOLYTIC ACTIVITY, PROCESS FOR THEIR PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS | LABORATORI GUIDOTTI S.P.A. (IT) | 1987-06-10 | — | — | EP | claimed |
| EP-0144519-A1 | 2',4'-Difluoro-4-hydroxy-(1,1'-diphenyl)-3-carboxylic derivatives of N-acetylcysteine and of S-carboxymethylcysteine having anti-inflammatory and mucolytic activity, process for their preparation and related pharmaceutical compositions | LABORATORI GUIDOTTI S.P.A. (IT) | 1985-06-19 | — | — | EP | claimed |
| EP-2155678-A1 | NEW BRADYKININ B1 ANTAGONISTS | EVOTEC Neurosciences GmbH (DE) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008125570-A1 | NEW BRADYKININ B1 ANTAGONISTS | EVOTEC NEUROSCIENCES GMBH (DE) | 2008-10-23 | — | — | WO | disclosed |