SCHEMBL3685147

SCHEMBL3685147

COC(=O)CSC[C@H](N)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC1A1 P43005 1/20 0.46
ARG1 P05089 1/20 0.46
ARG2 P78540 1/20 0.46
NOS2 P35228 3/20 0.45
NOS1 P29475 2/20 0.45
NOS3 P29474 1/20 0.45
KIF11 P52732 6/20 0.40
SLC7A5 Q01650 2/20 0.40
BHMT Q93088 2/20 0.38
GFPT1 Q06210 1/20 0.38
BHMT2 Q9H2M3 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3685144 1.00 SLC1A1 (0.46) SLC1A1ARG1ARG2NOS2NOS1
SCHEMBL3632964 0.85 KIF11 (0.41) SLC1A1KIF11
SCHEMBL28589135 0.83 ARG1 (0.53) SLC1A1ARG1ARG2NOS2NOS1
SCHEMBL28589137 0.83 ARG1 (0.53) SLC1A1ARG1ARG2NOS2NOS1
Hydrochloric Acid SCHEMBL10770246 0.83 KIF11 (0.40) SLC1A1KIF11
Hydrochloric Acid SCHEMBL11196457 0.83 KIF11 (0.40) SLC1A1KIF11
SCHEMBL27653685 0.83 GSR (0.49) SLC1A1ARG1ARG2NOS2NOS1
SCHEMBL10796639 0.81 CYP1A2 (0.46) SLC1A1ARG1ARG2NOS2NOS1
SCHEMBL30983358 0.80 ARG1 (0.42) ARG1ARG2NOS2NOS1NOS3
SCHEMBL7363488 0.80 ARG1 (0.42) ARG1ARG2NOS2NOS1NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021093733-A1 QUALITY CONTROL METHOD FOR CARBOCISTEINE RAW MATERIAL AND FORMULATION THEREOF, AND USE THEREOF 广东华南药业集团有限公司 2021-05-20 WO disclosed
US-8703750-B2 Mixtures and methods for the induction of resistance in plants ISAGRO S.P.A. (IT) 2014-04-22 US disclosed
CN-1925748-B Mixtures and methods for inducing resistance in plants ISAGRO SPA 2011-08-10 CN disclosed
US-20100317519-A1 Mixtures and methods for the induction of resistance in plants ISAGRO S.P.A. (IT) 2010-12-16 US disclosed
US-20070173459-A1 Mixtures and methods for the induction of resistance in plants ISAGRO S.P.A. (IT) 2007-07-26 US disclosed
CN-1925748-A Mixtures and methods for inducing resistance in plants ISAGRO SPA (IT) 2007-03-07 CN disclosed
EP-1720408-A1 MIXTURES AND METHODS FOR THE INDUCTION OF RESISTANCE IN PLANTS ISAGRO S.p.A. (IT) 2006-11-15 EP disclosed
WO-2005094580-A1 MIXTURES AND METHODS FOR THE INDUCTION OF RESISTANCE IN PLANTS ISAGRO S.P.A. (IT) 2005-10-13 WO disclosed
EP-0765340-B1 METHIONINE SULFONE AND S-SUBSTITUTED CYSTEINE SULFONE DERIVATIVES AS ENZYME INHIBITORS CORVAS INT INC (US) 2000-08-30 EP disclosed
US-5776927-A THROMBIN INHIBITORS CORVAS INTERNATIONAL, INC. (US) 1998-07-07 US disclosed
US-5770600-A Methionine sulfone and S-substituted cysteine sulfone derivatives as enzyme inhibitors CORVAS INTERNATIONAL, INC. (US) 1998-06-23 US disclosed
US-5681844-A ANTITHROMBOTIC AGENTS, ANTICOAGULANTS CORVAS INTERNATIONAL, INC. (US) 1997-10-28 US disclosed
US-5658939-A PREVENTION THROMBOSIS IN MAMMALS CORVAS INTERNATIONAL INC. (US) 1997-08-19 US disclosed
US-5646165-A ANTITHROMBOTIC AGENTS CORVAS INTERNATIONAL, INC. (US) 1997-07-08 US disclosed
EP-0765340-A1 METHIONINE SULFONE AND S-SUBSTITUTED CYSTEINE SULFONE DERIVATIVES AS ENZYME INHIBITORS CORVAS INTERNATIONAL, INC. (US) 1997-04-02 EP disclosed
WO-1995028420-A1 METHIONINE SULFONE AND S-SUBSTITUTED CYSTEINE SULFONE DERIVATIVES AS ENZYME INHIBITORS CORVAS INTERNATIONAL, INC. (US) 1995-10-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070173459-A1 Mixtures and methods for the induction of resistance in plants SLC11A2, MYD88, ME2 SLC1A1 3453/4885ARG1 1216/4885ARG2 1038/4885
US-20100317519-A1 Mixtures and methods for the induction of resistance in plants SLC11A2, MYD88, ME2 SLC1A1 3453/4885ARG1 1216/4885ARG2 1038/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.