Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CTH | P32929 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1124217 | 0.81 | TSHR (0.42) | L3MBTL1TSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL27457306 | 0.79 | EGLN1 (0.40) | EGLN1TSHRCTHAPEX1ALDH1A1 | |
| SCHEMBL10583654 | 0.74 | GAA (0.48) | TSHRALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL6925210 | 0.72 | — | — | |
| SCHEMBL17848859 | 0.71 | CYP3A4 (0.47) | TSHRALDH1A1LMNA | |
| SCHEMBL13575632 | 0.71 | L3MBTL1 (0.36) | L3MBTL1 | |
| SCHEMBL531168 | 0.69 | — | — | |
| SCHEMBL19525797 | 0.69 | — | — | |
| SCHEMBL11696223 | 0.68 | EGLN1 (0.39) | EGLN1TSHRCTHAPEX1ALDH1A1 | |
| Phosphoric Acid SCHEMBL28972551 | 0.67 | LMNA (0.39) | EGLN1TSHRCTHAPEX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152664-A1 | DIPEPTIDE ANALOGS AS COAGULATION FACTOR INHIBITORS | Brystol-Myers Squibb Company (US) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008157162-A1 | DIPEPTIDE ANALOGS AS COAGULATION FACTOR INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-12-24 | — | — | WO | disclosed |
| CN-1130404-A | Improved method of preparing glyoxylic acid/amino methy/phosphonic acid mixture using microbial double-transformant | DU PONT (US) | 1996-09-04 | — | — | CN | disclosed |