Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1170168 | 0.84 | GSR (0.36) | ALDH1A1CYP3A4HPGDGSRRNPEP | |
| SCHEMBL10749571 | 0.82 | GSR (0.39) | TSHRGSRRNPEPCPB2 | |
| SCHEMBL1170459 | 0.80 | THRB (0.39) | TSHRGSRTHRBRNPEPCPB2 | |
| SCHEMBL9716606 | 0.79 | GSR (0.39) | ALDH1A1GSRRNPEPCPB2 | |
| SCHEMBL9716610 | 0.79 | GSR (0.39) | ALDH1A1GSRRNPEPCPB2 | |
| SCHEMBL15208668 | 0.78 | CPB2 (0.38) | GSRRNPEPCPB2 | |
| SCHEMBL1170458 | 0.78 | CPB2 (0.35) | GSRRNPEPCPB2 | |
| SCHEMBL9716597 | 0.77 | CPB2 (0.46) | ALDH1A1HSD17B10GSRRNPEPCPB2 | |
| SCHEMBL9716594 | 0.77 | CPB2 (0.46) | ALDH1A1HSD17B10GSRRNPEPCPB2 | |
| SCHEMBL20788026 | 0.76 | GSR (0.44) | ALDH1A1GSRTHRBRNPEPCPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100311130-A1 | ENZYMATIC ESTER HYDROLYSIS | DSM IP ASSETS B.V. (NL) | 2010-12-09 | — | — | US | disclosed |
| EP-2155884-A1 | PROCESS FOR SELECTIVE ENZYMATIC HYDROLYSIS OF PENDANT ESTERS OF A POLYMER | DSM IP Assets B.V. (NL) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008155381-A1 | PROCESS FOR SELECTIVE ENZYMATIC HYDROLYSIS OF PENDANT ESTERS OF A POLYMER | DSM IP ASSETS B.V. (NL) | 2008-12-24 | — | — | WO | disclosed |