Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | EPOR | P19235 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716606 | 1.00 | GSR (0.39) | GSRRNPEPCPB2ALDH1A1MAPT | |
| SCHEMBL9716798 | 0.95 | ALDH1A1 (0.38) | GSRCPB2ALDH1A1MAPTGRIK1 | |
| SCHEMBL9716802 | 0.95 | ALDH1A1 (0.38) | GSRCPB2ALDH1A1MAPTGRIK1 | |
| SCHEMBL16862534 | 0.89 | ALDH1A1 (0.35) | GSRCPB2ALDH1A1MAPTGRIK1 | |
| SCHEMBL9716597 | 0.86 | CPB2 (0.46) | GSRRNPEPCPB2ALDH1A1MAPT | |
| SCHEMBL9716594 | 0.86 | CPB2 (0.46) | GSRRNPEPCPB2ALDH1A1MAPT | |
| SCHEMBL3826716 | 0.83 | ALDH1A1 (0.49) | ALDH1A1EPORITGB3ITGA2B | |
| SCHEMBL1170168 | 0.82 | GSR (0.36) | GSRRNPEPCPB2ALDH1A1MAPT | |
| SCHEMBL15208668 | 0.82 | CPB2 (0.38) | GSRRNPEPCPB2EPOR | |
| SCHEMBL9716651 | 0.81 | CYP1A2 (0.42) | GSRRNPEPCPB2ALDH1A1SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178911-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1992-01-22 | — | — | EP | disclosed |
| EP-0178911-A2 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |