Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 11/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.47 |
| ▸ | TNKS | O95271 | 3/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.47 |
| ▸ | PLD1 | Q13393 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.45 |
| ▸ | PLD2 | O14939 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3636808 | 0.85 | OPRM1 (0.65) | DRD2KCNH2OPRM1OPRK1OPRL1 | |
| SCHEMBL3666702 | 0.85 | OPRM1 (0.65) | DRD2KCNH2OPRM1OPRK1OPRL1 | |
| SCHEMBL1837392 | 0.83 | CALCRL (0.52) | CALCRLTNKSPARP1PARP2 | |
| SCHEMBL1837386 | 0.83 | CALCRL (0.52) | CALCRLTNKSPARP1PARP2 | |
| SCHEMBL3639475 | 0.82 | OPRM1 (0.61) | OPRM1OPRK1OPRL1PLD1PLD2 | |
| SCHEMBL27092740 | 0.82 | OPRM1 (0.69) | CALCRLDRD2KCNH2DRD4DRD3 | |
| SCHEMBL14046378 | 0.80 | DRD2 (0.56) | CALCRLDRD2KCNH2OPRM1OPRK1 | |
| SCHEMBL3635861 | 0.80 | OPRM1 (0.60) | DRD2KCNH2DRD4DRD3OPRM1 | |
| SCHEMBL3636443 | 0.76 | OPRM1 (0.47) | DRD2DRD4DRD3OPRM1OPRK1 | |
| SCHEMBL13380149 | 0.76 | CALCRL (0.56) | CALCRLDRD2KCNH2OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2160098-A2 | USE OF COMPOUNDS HAVING A MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE INHIBITORY ACTIVITY AS HERBICIDE OR ALGAECIDE, HERBICIDE AND ALGAECIDE COMPOSITIONS | Commissariat a L'Energie Atomique (FR) | 2010-03-10 | — | — | EP | disclosed |
| WO-2008146174-A2 | USE OF COMPOUNDS HAVING A MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE INHIBITORY ACTIVITY AS HERBICIDE OR ALGAECIDE, HERBICIDE AND ALGAECIDE COMPOSITIONS | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-12-04 | — | — | WO | disclosed |