Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 8/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3195755 | 0.83 | KDM1A (0.58) | KDM1AMAOAMAOB | |
| SCHEMBL4607730 | 0.80 | KDM1A (0.49) | KDM1AMAOAHRH3MAOBMMP3 | |
| SCHEMBL19585303 | 0.79 | KDM1A (0.67) | KDM1AMAOAMAOB | |
| SCHEMBL20020099 | 0.76 | KDM1A (0.45) | KDM1AHRH3 | |
| SCHEMBL14862100 | 0.75 | HTR3A (0.61) | — | |
| SCHEMBL5160136 | 0.75 | SLC18A3 (0.53) | KDM1AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL29051119 | 0.74 | HTR3A (0.59) | — | |
| SCHEMBL4607035 | 0.74 | GRIA4 (0.48) | KDM1AMAOAHRH3MAOB | |
| SCHEMBL7547980 | 0.73 | KDM1A (0.45) | KDM1AHRH3 | |
| SCHEMBL12976276 | 0.73 | KDM1A (0.63) | KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142505-A1 | SULFONAMIDES AND PHARMACEUTICAL COMPOSITIONS THEREOF | Pfizer, Inc. (US) | 2010-01-13 | — | — | EP | disclosed |
| WO-2008120093-A1 | SULFONAMIDES AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER INC. (US) | 2008-10-09 | — | — | WO | disclosed |