Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7906096 | 0.79 | HTR3A (0.58) | SLC6A2SLC6A4 | |
| SCHEMBL19341986 | 0.79 | KDM1A (0.50) | KDM1ADRD2DRD3SLC6A2SLC6A4 | |
| SCHEMBL19908542 | 0.79 | KDM1A (0.50) | KDM1ADRD2DRD3SLC6A2SLC6A4 | |
| SCHEMBL7547980 | 0.77 | KDM1A (0.45) | KDM1AGRIA4DRD2DRD3SLC6A2 | |
| SCHEMBL3633482 | 0.76 | KDM1A (0.46) | KDM1AHRH3 | |
| Hydrochloric Acid SCHEMBL31219767 | 0.75 | KDM1A (0.44) | KDM1AGRIA4DRD2DRD3SLC6A2 | |
| SCHEMBL14862100 | 0.75 | HTR3A (0.61) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL29051119 | 0.74 | HTR3A (0.59) | DRD2DRD3 | |
| SCHEMBL20899572 | 0.73 | LMNA (0.44) | GRIA4SLC6A2SLC6A4 | |
| SCHEMBL31385915 | 0.71 | NPC1 (0.46) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975025-B1 | THIOACETATE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | ARDEA BIOSCIENCES INC (US) | 2018-04-04 | — | — | EP | disclosed |