Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL939256 | 0.82 | XDH (0.39) | SMN1; SMN2ALDH1A1ALOX15RXFP1HPGD | |
| SCHEMBL6971332 | 0.76 | SCD (0.33) | SMN1; SMN2TSHRRXFP1HTTLMNA | |
| SCHEMBL6464252 | 0.76 | CFTR (0.44) | SMN1; SMN2TSHRALDH1A1RXFP1HTT | |
| SCHEMBL19066745 | 0.74 | — | — | |
| SCHEMBL4441896 | 0.70 | ALDH1A1 (0.37) | TSHRALDH1A1ALOX15HTTPOLB | |
| SCHEMBL28878067 | 0.68 | HTR2C (0.39) | SMN1; SMN2ALDH1A1ALOX15HTTLMNA | |
| SCHEMBL29967942 | 0.68 | HTR2C (0.39) | SMN1; SMN2ALDH1A1ALOX15HTTLMNA | |
| SCHEMBL3057644 | 0.68 | — | — | |
| SCHEMBL15264610 | 0.68 | — | — | |
| SCHEMBL1164338 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103108868-B | Furyl compounds and uses thereof | NOVOMEDIX, LLC (US) | 2015-11-25 | — | — | CN | disclosed |
| CN-104860907-A | Furanyl compounds and the use thereof | NOVOMEDIX LLC | 2015-08-26 | — | — | CN | disclosed |
| EP-2148868-A1 | NOVEL AROMATIC HETEROCYCLIC CARBOXYLIC ACID AMIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | NeuroSearch A/S (DK) | 2010-02-03 | — | — | EP | disclosed |
| WO-2008138917-A1 | NOVEL AROMATIC HETEROCYCLIC CARBOXYLIC ACID AMIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2008-11-20 | — | — | WO | disclosed |