Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971620 | 0.77 | SMN1; SMN2 (0.35) | SCDSMN1; SMN2RXFP1LMNAHTT | |
| SCHEMBL939256 | 0.77 | XDH (0.39) | SMN1; SMN2RXFP1HPGDCFTR | |
| SCHEMBL3633653 | 0.76 | SMN1; SMN2 (0.38) | SCDSMN1; SMN2RXFP1LMNAHTT | |
| SCHEMBL6464252 | 0.71 | CFTR (0.44) | SMN1; SMN2RXFP1LMNAHTTHPGD | |
| SCHEMBL6971991 | 0.68 | TP53 (0.36) | SMN1; SMN2HPGDTSHR | |
| SCHEMBL513905 | 0.67 | LMNA (0.55) | SMN1; SMN2LMNACES2 | |
| SCHEMBL18049534 | 0.62 | SMN1; SMN2 (0.37) | SMN1; SMN2RXFP1LMNAHTTHPGD | |
| SCHEMBL6968021 | 0.62 | CES2 (0.59) | HPGDTSHRCES2 | |
| SCHEMBL9625067 | 0.62 | KDM4E (0.50) | LMNAHPGD | |
| SCHEMBL18049526 | 0.59 | NOS3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | claimed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |