Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 10/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 8/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1715094 | 0.80 | KIT (0.49) | ADRA1AKIT | |
| SCHEMBL1715490 | 0.77 | KIT (0.44) | ALDH1A1SMN1; SMN2MEN1GAAKMT2A | |
| SCHEMBL1715861 | 0.77 | KIT (0.42) | MEN1KMT2AKDRABL1EGFR | |
| SCHEMBL1715659 | 0.76 | KIT (0.45) | ALDH1A1KDM4EKIT | |
| SCHEMBL1716300 | 0.76 | KDM4E (0.43) | ADRA1AADRA1DADRA1BALDH1A1KDM4E | |
| SCHEMBL1715790 | 0.76 | ABCC1 (0.42) | ALDH1A1KDM4ESMN1; SMN2MEN1GAA | |
| SCHEMBL3633866 | 0.75 | ADRA1A (0.40) | ADRA1AADRA1DADRA1BKDRABL1 | |
| SCHEMBL1715329 | 0.75 | KIT (0.40) | ADRA1AADRA1DADRA1BKDM4EKIT | |
| SCHEMBL1715290 | 0.74 | MAPK10 (0.49) | ALDH1A1KDM4EHPGDNPSR1HSD17B10 | |
| SCHEMBL1715456 | 0.74 | KIT (0.40) | ADRA1AADRA1DADRA1BKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146703-A1 | SRC FAMILY KINASE INHIBITORS | Leo Pharma A/S (DK) | 2010-01-27 | — | — | EP | claimed |
| WO-2008128538-A1 | SRC FAMILY KINASE INHIBITORS | LEO PHARMA A/S (DK) | 2008-10-30 | — | — | WO | claimed |