Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 13/20 | 0.49 |
| ▸ | BRAF | P15056 | 13/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1715490 | 0.82 | KIT (0.44) | KITBRAF | |
| SCHEMBL1715861 | 0.81 | KIT (0.42) | KITBRAF | |
| SCHEMBL1715659 | 0.81 | KIT (0.45) | KITBRAF | |
| SCHEMBL1715290 | 0.81 | MAPK10 (0.49) | KITBRAFPIK3C3 | |
| SCHEMBL3633868 | 0.80 | ADRA1A (0.41) | KITADRA1A | |
| SCHEMBL1715329 | 0.80 | KIT (0.40) | KITBRAFPIK3C3ADRA1A | |
| SCHEMBL1715456 | 0.79 | KIT (0.40) | KITBRAFADRA1A | |
| SCHEMBL1715873 | 0.79 | CCNE1 (0.38) | KITBRAFADRA1A | |
| SCHEMBL1715686 | 0.78 | KDM4E (0.44) | KITBRAFADRA1A | |
| SCHEMBL1716300 | 0.77 | KDM4E (0.43) | ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697312-B1 | HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF | LEO PHARMA AS (DK) | 2011-07-20 | — | — | EP | claimed |
| US-20100099710-A1 | SRC FAMILY KINASE INHIBITORS | JENSEN LENE | 2010-04-22 | — | — | US | claimed |
| EP-2146703-A1 | SRC FAMILY KINASE INHIBITORS | Leo Pharma A/S (DK) | 2010-01-27 | — | — | EP | claimed |
| WO-2008128538-A1 | SRC FAMILY KINASE INHIBITORS | LEO PHARMA A/S (DK) | 2008-10-30 | — | — | WO | claimed |
| US-20070244117-A1 | Novel Hydroxamic Acid Esters and Pharmaceutical Use Thereof | LEO PHARMA A/S (DK) | 2007-10-18 | — | — | US | claimed |
| JP-2007513098-A | — | — | 2007-05-24 | — | — | JP | claimed |
| EP-1697312-A2 | HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF | Leo Pharma A/S (DK) | 2006-09-06 | — | — | EP | claimed |
| WO-2005054179-A2 | HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF | LEO PHARMA A/S (DK) | 2005-06-16 | — | — | WO | claimed |
| US-20100099710-A1 | SRC FAMILY KINASE INHIBITORS | JENSEN LENE | 2010-04-22 | — | — | US | disclosed |
| EP-2146703-A1 | SRC FAMILY KINASE INHIBITORS | Leo Pharma A/S (DK) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008128538-A1 | SRC FAMILY KINASE INHIBITORS | LEO PHARMA A/S (DK) | 2008-10-30 | — | — | WO | disclosed |
| US-20070244117-A1 | Novel Hydroxamic Acid Esters and Pharmaceutical Use Thereof | LEO PHARMA A/S (DK) | 2007-10-18 | — | — | US | disclosed |
| EP-1697312-A2 | HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF | Leo Pharma A/S (DK) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005054179-A2 | HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF | LEO PHARMA A/S (DK) | 2005-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099710-A1 | SRC FAMILY KINASE INHIBITORS | SRC, FYN, LYN | KIT 435/4885BRAF 258/4885OPRM1 1904/4885 |
| US-20070244117-A1 | Novel Hydroxamic Acid Esters and Pharmaceutical Use Thereof | F9, F12, HDAC9 | KIT 406/4885BRAF 1422/4885OPRM1 3195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.