Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14108456 | 0.83 | ALDH1A1 (0.45) | NR3C2ALDH1A1ESR1ACP3MEN1 | |
| SCHEMBL12329342 | 0.83 | NR3C2 (0.42) | NR3C2ALDH1A1ESR1ACP3MEN1 | |
| SCHEMBL29048166 | 0.83 | ALDH1A1 (0.45) | NR3C2ALDH1A1ESR1ACP3MEN1 | |
| SCHEMBL6841260 | 0.83 | FFAR1 (0.49) | ACP3CTSA | |
| SCHEMBL11088063 | 0.83 | ALDH1A1 (0.45) | NR3C2ALDH1A1ESR1ACP3MEN1 | |
| SCHEMBL185405 | 0.82 | ALDH1A1 (0.42) | NR3C2ALDH1A1ESR1ACP3MEN1 | |
| SCHEMBL29998155 | 0.82 | ALDH1A1 (0.42) | NR3C2ALDH1A1ESR1ACP3MEN1 | |
| SCHEMBL16232166 | 0.81 | NR3C2 (0.41) | NR3C2ALDH1A1ESR1ACP3MEN1 | |
| SCHEMBL14046834 | 0.81 | TSHR (0.60) | ALDH1A1MAPTTSHRCYP2C19HPGD | |
| SCHEMBL17755029 | 0.81 | NR3C2 (0.41) | NR3C2ALDH1A1ESR1ACP3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |