SCHEMBL29048166

SCHEMBL29048166

Cc1ccccc1C(CC(N)=O)c1ccccc1C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
CYP2C19 P33261 3/20 0.45
ACP3 P15309 1/20 0.43
NR3C2 P08235 1/20 0.43
NPSR1 Q6W5P4 2/20 0.42
CYP1A2 P05177 2/20 0.42
CYP2D6 P10635 1/20 0.42
PKM P14618 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ESR1 P03372 1/20 0.41
CTSA P10619 5/20 0.40
POLB P06746 1/20 0.40
HTT P42858 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MEN1 O00255 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
HPGD P15428 1/20 0.39
KMT2A Q03164 1/20 0.39
GABBR2 O75899 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11088063 0.89 ALDH1A1 (0.45) ALDH1A1CYP2C19ACP3NR3C2NPSR1
SCHEMBL14108456 0.85 ALDH1A1 (0.45) ALDH1A1CYP2C19ACP3NR3C2NPSR1
SCHEMBL2794839 0.84 CTSA (0.49) ACP3CTSAGABBR2GABBR1
SCHEMBL185424 0.84 ALDH1A1 (0.42) ALDH1A1CYP2C19ACP3NR3C2NPSR1
SCHEMBL363392 0.83 NR3C2 (0.47) ALDH1A1CYP2C19ACP3NR3C2NPSR1
SCHEMBL185645 0.81 ALDH1A1 (0.40) ALDH1A1ACP3NR3C2NPSR1CYP1A2
SCHEMBL29998155 0.80 ALDH1A1 (0.42) ALDH1A1CYP2C19ACP3NR3C2NPSR1
SCHEMBL185405 0.80 ALDH1A1 (0.42) ALDH1A1CYP2C19ACP3NR3C2NPSR1
SCHEMBL30781885 0.78 GABBR2 (0.48) ACP3NPSR1CTSAPOLBHTT
SCHEMBL658439 0.78 GABBR2 (0.48) ACP3NPSR1CTSAPOLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116547266-A Synthesis method of anthranilic acid/amide compound and intermediate thereof 皮埃企业有限公司 2023-08-04 CN disclosed