Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PNP | P00491 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3637817 | 0.88 | DGAT1 (0.33) | DGAT1NPC1 | |
| SCHEMBL6545264 | 0.87 | DGAT1 (0.32) | DGAT1 | |
| SCHEMBL9584122 | 0.84 | DGAT1 (0.31) | DGAT1 | |
| SCHEMBL3640575 | 0.83 | DGAT1 (0.31) | DGAT1 | |
| SCHEMBL3634283 | 0.81 | MEN1 (0.34) | DGAT1 | |
| SCHEMBL30720870 | 0.80 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL3809059 | 0.80 | DUT (0.33) | DGAT1 | |
| SCHEMBL30720869 | 0.80 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL67719 | 0.79 | DGAT1 (0.35) | DGAT1NPC1PNP | |
| SCHEMBL17895929 | 0.78 | DGAT1 (0.31) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304419-B2 | Chemical compounds | GLAXOSMITHKLINE LLC (US) | 2012-11-06 | — | — | US | disclosed |
| EP-2166856-A1 | CHEMICAL COMPOUNDS | GlaxoSmithKline LLC (US) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008154271-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-12-18 | — | — | WO | disclosed |